Differences in ultrasonic vocalizations between wild and laboratory California mice (Peromyscus californicus).
Differences in ultrasonic vocalizations between wild and laboratory California mice (Peromyscus californicus).
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DOI：
10.1371/journal.pone.0009705
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发表时间：
2010-04-01
期刊：
影响因子：
3.7
通讯作者：
Crossland JP
中科院分区：
文献类型：
--
作者：
Kalcounis-Rueppell MC;Petric R;Briggs JR;Carney C;Marshall MM;Willse JT;Rueppell O;Ribble DO;Crossland JP
鼠类啮齿动物（包括实验室小鼠和大鼠）发出的超声发声（USV）被用作行为测定和生物医学研究中的表型标记物。对这些USV的解释取决于对野生啮齿动物产生USV的意义的理解。然而，迄今为止，还没有关于野生啮齿动物超声功能的研究，并且缺乏野生啮齿动物和实验室啮齿动物产生的USV的比较。在这里，我们报告的野生和圈养啮齿动物USVs记录从同一物种，Peromyscus californicus的第一次比较。我们使用标准超声记录技术测量来自实验室（Peromyscus Genetic Stock Center，SC，USA）和野生（Hastings Natural History Reserve，CA，USA）的加州小鼠的USV。为了确定哪只加州小鼠在野外发声，我们使用了一种遥感方法，该方法使用了12个麦克风的声学定位阵列，并结合了声学定位阵列区域内所有居民Peromyscus californicus的自动无线电遥测。实验室中的加州小鼠和野生小鼠产生了相同类型的USV基序。然而，野生加州小鼠产生的USV中位频率比实验室加州小鼠高2-8 kHz，并且频率变化显著更大。来自野生和实验室加州小鼠的USV的总体形式的相似性表明，圈养的鹿鼠产生USV不是圈养的人工产物。我们的研究验证了USV在实验室啮齿动物中作为行为指标的广泛使用，但强调了实验室USV的特定特征可能无法反映自然条件。
Ultrasonic vocalizations (USVs) emitted by muroid rodents, including laboratory mice and rats, are used as phenotypic markers in behavioral assays and biomedical research. Interpretation of these USVs depends on understanding the significance of USV production by rodents in the wild. However, there has never been a study of muroid rodent ultrasound function in the wild and comparisons of USVs produced by wild and laboratory rodents are lacking to date. Here, we report the first comparison of wild and captive rodent USVs recorded from the same species, Peromyscus californicus. We used standard ultrasound recording techniques to measure USVs from California mice in the laboratory (Peromyscus Genetic Stock Center, SC, USA) and the wild (Hastings Natural History Reserve, CA, USA). To determine which California mouse in the wild was vocalizing, we used a remote sensing method that used a 12-microphone acoustic localization array coupled with automated radio telemetry of all resident Peromyscus californicus in the area of the acoustic localization array. California mice in the laboratory and the wild produced the same types of USV motifs. However, wild California mice produced USVs that were 2–8 kHz higher in median frequency and significantly more variable in frequency than laboratory California mice. The similarity in overall form of USVs from wild and laboratory California mice demonstrates that production of USVs by captive Peromyscus is not an artifact of captivity. Our study validates the widespread use of USVs in laboratory rodents as behavioral indicators but highlights that particular characteristics of laboratory USVs may not reflect natural conditions.
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影响因子：
2.6
作者：
Brudzynski, SM
通讯作者：
Brudzynski, SM
影响因子：
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Lee, Anna W.;Brown, Richard E.
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作者：
Bredy, TW;Lee, AW;Brown, RE
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Brown, RE
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GUTTINGER, HR
通讯作者：
GUTTINGER, HR
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2.8
作者：
Kalcounis-Rueppell MC;Metheny JD;Vonhof MJ
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