Trends in homelessness and injection practices among young urban and suburban people who inject drugs: 1997-2017.
Trends in homelessness and injection practices among young urban and suburban people who inject drugs: 1997-2017.
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DOI：
10.1016/j.drugalcdep.2021.108797
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发表时间：
2021-08-01
影响因子：
4.2
通讯作者：
Boodram, Basmattee
中科院分区：
文献类型：
--
作者：
Hotton, Anna;Mackesy-Amiti, Mary-Ellen;Boodram, Basmattee
在注射吸毒的年轻人 (PWID) 中，无家可归与许多不良的社会心理和健康后果有关，包括复发和吸毒过量的风险、心理困扰和自杀、治疗机会有限以及增加艾滋病毒和丙型肝炎 (HCV) 传播风险的注射行为。无家可归的注射吸毒者也不太可能通过药房或注射器服务计划获得无菌注射器。本研究利用 1997 年至 2017 年间收集的 11 项研究的数据，应用随机效应元回归来检验芝加哥及周边郊区和农村地区年轻注射吸毒者注射风险行为和无家可归的随时间变化的趋势。此外，汇集了受试者水平的数据，使用混合效应 Logistic 和负二项式回归与随机研究效应来评估所有研究中无家可归对风险行为的影响。随着时间的推移，年轻注射吸毒者的无家可归人数显着增加，这与青少年无家可归人数增加的总体趋势一致。在混合效应回归中，无家可归与注射风险行为（共享注射器、注射器介导的共享、设备共享）和交换性行为有关，尽管我们没有发现风险行为随时间的总体变化。随着时间的推移，年轻注射吸毒者无家可归的情况不断增加，这突出表明需要进行研究，以了解导致青少年无家可归的因素，以便为该人群提供艾滋病毒/性传播感染、丙型肝炎病毒和药物过量预防和干预服务。
Among young people who inject drugs (PWID) homelessness is associated with numerous adverse psychosocial and health consequences, including risk of relapse and overdose, psychological distress and suicidality, limited treatment access, and injection practices that increase the risk of HIV and hepatitis C (HCV) transmission. Homeless PWID may also be less likely to access sterile syringes through pharmacies or syringe service programs. This study applied random-effects meta-regression to examine trends over time in injection risk behaviors and homelessness among young PWID in Chicago and surrounding suburban and rural areas using data from 11 studies collected between 1997 and 2017. In addition, subject-level data were pooled to evaluate the effect of homelessness on risk behaviors across all studies using mixed effects logistic and negative binomial regression with random study effects. There was a significant increase in homelessness among young PWID over time, consistent with the general population trend of increasing youth homelessness. In mixed-effects regression, homelessness was associated with injection risk behaviors (receptive syringe sharing, syringe mediated sharing, equipment sharing) and exchange sex, though we detected no overall changes in risk behavior over time. Increases over time in homelessness among young PWID highlight a need for research to understand factors contributing to youth homelessness to inform HIV/STI, HCV, and overdose prevention and intervention services for this population.
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影响因子：
4.2
作者：
Linton, Sabriya L.;Celentano, David D.;Mehta, Shruti H.
通讯作者：
Mehta, Shruti H.
DOI：
10.1007/s11524-010-9534-5
发表时间：
2011-04-01
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作者：
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