The biological response to orthopaedic implants for joint replacement: Part I: Metals.
The biological response to orthopaedic implants for joint replacement: Part I: Metals.
复制标题
DOI：
10.1002/jbm.b.33734
复制
发表时间：
2017-10
期刊：
影响因子：
--
通讯作者：
Goodman SB
中科院分区：
文献类型：
--
作者：
Gibon E;Amanatullah DF;Loi F;Pajarinen J;Nabeshima A;Yao Z;Hamadouche M;Goodman SB
关节置换术是一种常见的、非常成功的骨科手术，外科医生有很多不同的材料和植入物设计可供选择。用于关节置换的材料必须具有生物学可接受性，以最大限度地减少不良局部组织反应，并且足够坚固，以支持日常生活中的日常活动。现代关节置换由金属及其合金、聚合物、陶瓷和复合材料制成。本文综述了关节置换术中不同生物材料的生物学反应。一般来说，用于关节置换的现代材料只要是散装（而不是颗粒或离子）形式，机械稳定且无感染，身体就能很好地耐受。如果不满足后一条件，假体将与急性/慢性炎症反应、假体周围骨质溶解、松动和失效相关。本文（第1部分，共2部分）致力于骨科手术中金属器械的使用，包括对金属副产物的相关生物学反应，是对该主题相关基础科学文献的综述。
Joint replacement is a commonly performed, highly successful orthopaedic procedure, for which surgeons have a large choice of different materials and implant designs. The materials used for joint replacement must be both biologically acceptable to minimize adverse local tissue reactions, and robust enough to support weight bearing during common activities of daily living. Modern joint replacements are made from metals and their alloys, polymers, ceramics, and composites. This review focuses on the biological response to the different biomaterials used for joint replacement. In general, modern materials for joint replacement are well tolerated by the body as long as they are in bulk (rather than in particulate or ionic) form, are mechanically stable and noninfected. If the latter conditions are not met, the prosthesis will be associated with an acute/chronic inflammatory reaction, peri-prosthetic osteolysis, loosening and failure. This article (Part 1 of 2) is dedicated to the use of metallic devices in orthopaedic surgery including the associated biological response to metallic byproducts is a review of the basic science literature regarding this topic.
登录
查看更多内容
DOI：
10.1302/0301-620x.83b7.10102
发表时间：
2001-09-01
影响因子：
--
作者：
Doherty, AT;Howell, RT;Case, CP
通讯作者：
Case, CP
影响因子：
4.2
作者：
Campbell, Patricia A.;Kung, Michael S.;Jacobs, Joshua J.
通讯作者：
Jacobs, Joshua J.
影响因子：
2.8
作者：
Cadosch, Dieter;Chan, Erwin;Filgueira, Luis
通讯作者：
Filgueira, Luis
影响因子：
--
作者：
Adala, Raviraj;Chakravarthy, Murali;Pai, Sanjay
通讯作者：
Pai, Sanjay
影响因子：
1.8
作者：
De Smet, KA
通讯作者：
De Smet, KA