COVID-19 and hypertension: risks and management. A scientific statement on behalf of the British and Irish Hypertension Society.
COVID-19 and hypertension: risks and management. A scientific statement on behalf of the British and Irish Hypertension Society.
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DOI：
10.1038/s41371-020-00451-x
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发表时间：
2021-04
影响因子：
2.7
通讯作者：
Martin U
中科院分区：
文献类型：
--
作者：
Clark CE;McDonagh STJ;McManus RJ;Martin U
高血压是全球残疾调整生命年损失的最大单一贡献者[1]。大多数60岁以上的人群患有高血压[2]，并且有人认为他们可能会受到COVID-19影响的风险增加。尽管如此，也许是由于其在老年人群中的普遍存在，目前英国政府的指导并没有将高血压患者确定为高危人群[3]，然而，其他机构，如英国心脏基金会和爱尔兰的卫生服务执行机构[4，5]。本文旨在总结和解释目前支持和反对血压升高患者COVID-19风险和严重程度增加的证据，并讨论抗高血压治疗选择的意义。早期的小型病例系列并未表明因COVID-19入院的患者高血压过度[6]。新型冠状病毒肺炎应急响应流行病学小组发表了来自中国的大型病例系列;他们发现总体病死率为2.3%（44，672例确诊病例中的1023例），高血压患者的病死率增加到6.0%[7]。报告这些数据时未对年龄进行调整。COVID-19病死率和高血压患病率均随年龄增长而增加，70-79岁人群分别达到8.0%和50%以上
Hypertension is the single largest global contributor to disability-adjusted life years lost [1]. The majority of the population aged over 60 years have hypertension [2], and it has been suggested that they may be at increased risk from the effects of COVID-19. Despite this, and perhaps due to its ubiquity in the older population, current UK Government guidance does not identify people with hypertension as ʻat risk’[3], however, other bodies such as the British Heart Foundation and the Health Service Executive in Ireland do [4, 5]. This article seeks to summarise and interpret the current evidence for and against an increase in COVID-19 risk and severity for those with raised blood pressure, and discusses the implications for the choice of antihypertensive treatment.Early small case series did not indicate an excess of hypertension in people admitted to hospital with COVID-19 [6]. The Novel Coronavirus Pneumonia Emergency Response Epidemiology Team published a large case series from China; they found an overall case fatality rate of 2.3%(1023 of 44,672 confirmed cases), which increased to 6.0% for people with hypertension [7]. These data were reported without adjustment for age. Both COVID-19 case fatality rates and hypertension prevalence increase with age, reaching 8.0% and over 50% respectively for the 70–79
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DOI：
10.20452/pamw.15272
发表时间：
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