Photoacoustic spectrum analysis for microstructure characterization in biological tissue: analytical model.
Photoacoustic spectrum analysis for microstructure characterization in biological tissue: analytical model.
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DOI:
10.1016/j.ultrasmedbio.2015.01.010
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发表时间:
2015-05
影响因子:
2.9
通讯作者:
Wang, Xueding
中科院分区:
文献类型:
--
作者:
Xu, Guan;Fowlkes, J. Brian;Tao, Chao;Liu, Xiaojun;Wang, Xueding
Photoacoustic spectrum analysis (PASA) has demonstrated the capability of identifying the microstructures in phantoms and biological tissues. PASA adopts the procedures in ultrasound (US) spectrum analysis although the signal generation mechanisms related to ultrasound backscatter and photoacoustic wave generation differ. The purpose of this study is to theoretically validate the method of PASA. The analytical solution to the power spectrum of PA signals generated by identical microspheres following discrete uniform random distribution in space was derived. The simulation and experiment validation of analytical solution include: 1) the power spectrum profile of a single microsphere with a diameter of 300 μm; and 2) the PASA parameters of the PA signals generated by randomly distributed microspheres of diameters of 100, 200, 300, 400 and 500 μm, and at concentrations of 30, 60, 120, 240, 480 per 1.53cm3 in the observation range of [0.5, 13MHz].
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影响因子:
--
作者:
HEIDEN, C
通讯作者:
HEIDEN, C
影响因子:
2.4
作者:
Hoelen, CGA;de Mul, FFM
通讯作者:
de Mul, FFM
影响因子:
4
作者:
Yang, Yiqun;Wang, Shaohua;Liu, Xiaojun
通讯作者:
Liu, Xiaojun
影响因子:
4
作者:
Xu, Guan;Dar, Irfaan A.;Wang, Xueding
通讯作者:
Wang, Xueding
影响因子:
4
作者:
Wang, Shaohua;Tao, Chao;Liu, Xiaojun
通讯作者:
Liu, Xiaojun