A comparative study on cephalometric differences in maxillofacial morphology between skeletal Class III cases with and without acromegaly: a pilot study
A comparative study on cephalometric differences in maxillofacial morphology between skeletal Class III cases with and without acromegaly: a pilot study
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伴肢端肥大症与不伴肢端肥大症的骨骼Ⅲ类病例颌面部形态头影测量差异的比较研究：一项初步研究
DOI：
10.1007/s11282-021-00548-0
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发表时间：
2021
期刊：
影响因子：
2.2
通讯作者：
Iikubo Masahiro
中科院分区：
文献类型：
--
作者：
Tanaka Atsushi;Shoji Noriaki;Kojima Ikuho;Kumasaka Akira;Sakamoto Maya;Sasaki Kiyo;Fukunaga Tomohiro;Mizoguchi Itaru;Tominaga Teiji;Iikubo Masahiro
目的肢端肥大症患者最典型的颌面特征是下颌突出。本研究旨在通过头颅测量分析确定患有和不患有肢端肥大症的骨骼III类患者颌面形态的差异。方法回顾性收集37例肢端肥大症（Acro）患者、37例年龄匹配的非肢端肥大症伴骨骼III类错颌合（C-III）患者和37例年龄匹配的ⅰ类错颌合（C-I）患者的脑电图资料。每组的骨骼和牙齿形态分析使用头测量分析，包括线性和角度测量和面部轮廓图。此外，我们使用受试者工作特征（ROC）曲线分析区分肢端肥大症和骨骼III类错颌畸形的诊断性能和临界值。结果Acro组的下颌支高度明显高于其他组。Acro组L1/MP的增加是本研究中最显著的特征，它代表了下颌中切牙的唇倾。ROC曲线分析显示，L1/MP的截断值为88.4°，在区分肢端肥大症和非肢端肥大症III类错颌畸形方面具有最高的诊断效能。结论肢端肥大症比非肢端肥大症有更大程度的双颌前突。关注下颌中切牙的唇倾是鉴别肢端肥大症和非肢端肥大症III类错颌畸形的最有用的方法。
ObjectivesThe most typical maxillofacial feature of patients with acromegaly is mandibular protrusion. This study aimed to determine differences in maxillofacial morphology between skeletal Class III patients with and without acromegaly using cephalometric analysis.MethodsCephalograms of 37 patients with acromegaly (Acro), 37 age-matched non-acromegalic patients with skeletal Class III malocclusion (C-III), and 37 age-matched Class I malocclusion patients (C-I; control) were retrospectively collected. The skeletal and dental morphology of each group was analyzed using cephalometric analysis, which included linear and angular measurements and facial profilograms. In addition, we analyzed diagnostic performance and cutoff values for discriminating acromegaly from skeletal Class III malocclusion using receiver operating characteristic (ROC) curve analysis.ResultsThe mandibular ramus height was larger in the Acro group than in the other groups. The increase in L1/MP in the Acro group, which represented labial inclination of the mandibular central incisors, was the most characteristic feature in this study. ROC curve analysis indicated that a cutoff value of 88.4° for L1/MP had the highest diagnostic performance in discriminating acromegaly from non-acromegalic Class III malocclusion.ConclusionsAcromegaly was characterized by a greater degree of bimaxillary prognathism than was non-acromegalic Class III malocclusion. Focusing on labial inclination of the mandibular central incisors would be the most useful way to differentiate acromegaly from non-acromegalic Class III malocclusion.
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DOI：
--
发表时间：
2019
期刊：
Odontoestomatología
影响因子：
--
作者：
Tomás Freundlich;David Arueste;G. Manríquez;A. Díaz
通讯作者：
A. Díaz
影响因子：
--
作者：
Atreja G;Atreja SH;Jain N;Sukhija U
通讯作者：
Sukhija U
DOI：
10.1016/j.ajodo.2004.08.018
发表时间：
2005-12-01
影响因子：
3
作者：
Janson, G;de Souza, JEP;Henriques, JFC
通讯作者：
Henriques, JFC
影响因子：
1.3
作者：
B. Solow
通讯作者：
B. Solow
肢端肥大症牙科患者：病例报告。
影响因子：
1.9
作者：
R. Kashyap;G. Babu;S. Shetty
通讯作者：
S. Shetty