Understanding dengue virus evolution to support epidemic surveillance and counter-measure development.
Understanding dengue virus evolution to support epidemic surveillance and counter-measure development.
复制标题
了解登革热病毒的进化,以支持流行病监测和相对生长的发展。
DOI:
10.1016/j.meegid.2018.04.032
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发表时间:
2018-08
期刊:
影响因子:
--
通讯作者:
Jarman RG
中科院分区:
文献类型:
--
作者:
Pollett S;Melendrez MC;Maljkovic Berry I;Duchêne S;Salje H;Cummings DAT;Jarman RG
Dengue virus (DENV) causes a profound burden of morbidity and mortality, and its global burden is rising due to the co-circulation of four divergent DENV serotypes in the ecological context of globalization, travel, climate change, urbanization, and expansion of the geographic range of the Ae.aegypti and Ae.albopictus vectors. Understanding DENV evolution offers valuable opportunities to enhance surveillance and response to DENV epidemics via advances in RNA virus sequencing, bioinformatics, phylogenetic and other computational biology methods. Here we provide a scoping overview of the evolution and molecular epidemiology of DENV and the range of ways that evolutionary analyses can be applied as a public health tool against this arboviral pathogen.
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