Ocular VEMPs indicate repositioning of otoconia to the utricle after successful liberatory maneuvers in benign paroxysmal positioning vertigo.

Ocular VEMPs indicate repositioning of otoconia to the utricle after successful liberatory maneuvers in benign paroxysmal positioning vertigo.
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DOI:
10.3109/00016489.2013.829922
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发表时间:
2013-12
影响因子:
1.4
通讯作者:
Strupp M
Strupp M
中科院分区:
医学4区
文献类型:
--
作者:
Bremova T;Bayer O;Agrawal Y;Kremmyda O;Brandt T;Teufel J;Strupp M

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这项研究表明,在成功的解放演习后,受影响的耳朵的眼前庭诱发肌源性电位(oVEMP)振幅的短暂增加和颈部VEMP(cVEMP)振幅没有变化。这些发现支持了这一假设,即成功的解放演习可以导致重新定位耳石的椭圆囊。评估后半规管良性阵发性定位性眩晕(pc-BPPV)患者成功解脱后oVEMP振幅是否增加,而cVEMP振幅没有变化。这些发现可能表明,成功地将脱位的耳石复位到椭圆囊黄斑,而不是囊状黄斑。30例单侧pc-BPPV患者在4个时间点进行了骨导oVEMP和空气导cVEMP前瞻性检查:解放演习(Sémont演习)之前,之后,1周后和1个月后。在1周随访时,30例患者中有20例无症状(应答者);其余10例(无应答者)仍可诱导BPPV。在应答者中,受累侧的平均n10振幅从基线(治疗前)的12 ± 6.5 μV增加至治疗后1周的15.9 ± 7.1 μV;应答者的增加显著(p = 0.001)高于非应答者。cVEMP无显著差异。
This study showed a transient increase of ocular vestibular evoked myogenic potential (oVEMP) amplitudes in the affected ear after successful liberatory maneuvers and no changes in cervical VEMP (cVEMP) amplitudes. These findings support the hypothesis that successful liberatory maneuvers can lead to a repositioning of otoconia to the utricle. To evaluate whether oVEMP amplitudes increase after successful liberatory maneuvers in patients with posterior semicircular canal benign paroxysmal positioning vertigo (pc-BPPV), while cVEMP amplitudes do not change. These findings may indicate a successful repositioning of dislodged otoconia to the utricular macula, but not to the saccular macula. Thirty patients with unilateral pc-BPPV were prospectively examined with bone-conducted oVEMP and air-conducted cVEMP at four time points: before, after, 1 week after, and 1 month after the liberatory maneuvers (Sémont maneuvers). At the 1-week follow-up, 20 of 30 patients were asymptomatic (responders); BPPV could still be induced in the other 10 (non-responders). In responders the mean n10 amplitude on the affected side increased from 12 ± 6.5 μV at baseline (before the treatment) to 15.9 ± 7.1 μV at 1 week after treatment; this increase was significantly (p = 0.001) higher in responders than in non-responders. cVEMP did not differ significantly.
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