Genome-wide identification and mapping of NBS-encoding resistance genes in Solanum tuberosum group phureja.
Genome-wide identification and mapping of NBS-encoding resistance genes in Solanum tuberosum group phureja.
复制标题
DOI:
10.1371/journal.pone.0034775
复制
发表时间:
2012
期刊:
影响因子:
3.7
通讯作者:
Orjeda G
中科院分区:
文献类型:
--
作者:
Lozano R;Ponce O;Ramirez M;Mostajo N;Orjeda G
The majority of disease resistance (R) genes identified to date in plants encode a nucleotide-binding site (NBS) and leucine-rich repeat (LRR) domain containing protein. Additional domains such as coiled-coil (CC) and TOLL/interleukin-1 receptor (TIR) domains can also be present. In the recently sequenced Solanum tuberosum group phureja genome we used HMM models and manual curation to annotate 435 NBS-encoding R gene homologs and 142 NBS-derived genes that lack the NBS domain. Highly similar homologs for most previously documented Solanaceae R genes were identified. A surprising ∼41% (179) of the 435 NBS-encoding genes are pseudogenes primarily caused by premature stop codons or frameshift mutations. Alignment of 81.80% of the 577 homologs to S. tuberosum group phureja pseudomolecules revealed non-random distribution of the R-genes; 362 of 470 genes were found in high density clusters on 11 chromosomes.
登录
查看更多内容
影响因子:
3.7
作者:
Massa AN;Childs KL;Lin H;Bryan GJ;Giuliano G;Buell CR
通讯作者:
Buell CR
影响因子:
5.8
作者:
Kozik, A;Kochetkova, E;Michelmore, R
通讯作者:
Michelmore, R
影响因子:
5.8
作者:
Delorenzi, M;Speed, T
通讯作者:
Speed, T
影响因子:
7.2
作者:
Ballvora, A;Ercolano, MR;Gebhardt, C
通讯作者:
Gebhardt, C
影响因子:
7.3
作者:
Douchkov, D;Gryczka, C;Bäumlein, H
通讯作者:
Bäumlein, H