Immunohistochemical analysis of human adenocarcinoma-associated antigen YH206 detected by a monoclonal antibody.
Immunohistochemical analysis of human adenocarcinoma-associated antigen YH206 detected by a monoclonal antibody.
复制标题
单克隆抗体检测人腺癌相关抗原YH206的免疫组织化学分析。
DOI:
--
复制
发表时间:
1986
期刊:
影响因子:
--
通讯作者:
Y. Hinoda
中科院分区:
文献类型:
--
作者:
A. Yachi;K. Imai;T. Endo;Y. Hinoda
A monoclonal antibody YH206 (IgM, kappa) was prepared using human lung adenocarcinoma A549 cell line as an immunogen. The histological distribution of antigenic determinant of the YH206 antigen was highly restricted to adenocarcinomas of various organs including the lung, the pancreas and the stomach, but it did not react with 10 cases of colonic adenocarcinomas by the immunoperoxidase technique. It did not stain non-cancerous tissues of 16 different organs, except for the renal tubules and for the secreting glands of the pancreas with which the antibody faintly reacts. It did not react with either granulocytes, lymphocytes or red blood cells. Positive staining was observed in various fetal tissues. Periodic acid and neuraminidase treatments on tissue sections suggested that the chemical nature of the antigenic determinant of YH206 antigen was carbohydrate in nature which might be masked by sialic acids.
登录
查看更多内容
影响因子:
11.2
作者:
J. Magnani;Z. Steplewski;H. Koprowski;V. Ginsburg
通讯作者:
J. Magnani;Z. Steplewski;H. Koprowski;V. Ginsburg
DOI:
10.1016/s0021-9258(19)45389-1
发表时间:
1982-12
期刊:
The Journal of biological chemistry
影响因子:
--
作者:
John L. MagnaniS;Bo Nilssong;Manfred BrockhausSV;David Zopfl;Zenon SteplewskiJI;Hilary Koprowskill;V. Ginsburg
通讯作者:
John L. MagnaniS;Bo Nilssong;Manfred BrockhausSV;David Zopfl;Zenon SteplewskiJI;Hilary Koprowskill;V. Ginsburg
影响因子:
11.2
作者:
K. Fukushima;M. Hirota;P. Terasaki;A. Wakisaka;H. Togashi;D. Chia;N. Suyama;Y. Fukushi;E. Nudelman;S. Hakomori
通讯作者:
K. Fukushima;M. Hirota;P. Terasaki;A. Wakisaka;H. Togashi;D. Chia;N. Suyama;Y. Fukushi;E. Nudelman;S. Hakomori
影响因子:
11.2
作者:
Mazauric,T;Mitchell,KF;Letchworth3rd,GJ;Koprowski,H;Steplewski,Z
通讯作者:
Steplewski,Z
影响因子:
11.2
作者:
Varki,NM;Reisfeld,RA;Walker,LE
通讯作者:
Walker,LE