Hypertension awareness, treatment, and control in adults with CKD: results from the Chronic Renal Insufficiency Cohort (CRIC) Study.
Hypertension awareness, treatment, and control in adults with CKD: results from the Chronic Renal Insufficiency Cohort (CRIC) Study.
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DOI：
10.1053/j.ajkd.2009.09.014
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发表时间：
2010-03
期刊：
影响因子：
--
通讯作者：
Chronic Renal Insufficiency Cohort (CRIC) Study Investigators
中科院分区：
文献类型：
--
作者：
Muntner P;Anderson A;Charleston J;Chen Z;Ford V;Makos G;O'Connor A;Perumal K;Rahman M;Steigerwalt S;Teal V;Townsend R;Weir M;Wright JT Jr;Chronic Renal Insufficiency Cohort (CRIC) Study Investigators
据报道，慢性肾病（CKD）患者的血压控制率较低。这些数据来自 CKD 知晓率较低的人群样本。对慢性肾功能不全队列 (CRIC) 研究 (n=3612) 基线访视的横断面数据进行了分析。通过医生办公室和实验室数据库审查确定了估计肾小球滤过率为 20 至 70 ml/min/1.73m2 的参与者。高血压的患病率和认识、治疗模式、控制率以及与高血压控制相关的因素。按照标准化方案，由经过培训的工作人员测量血压 3 次，高血压定义为收缩压≥140 mmHg 和/或舒张压≥90 mmHg 和/或自我报告的抗高血压药物使用情况。通过自我报告确定患者对高血压的认识和治疗，并评估两个水平的高血压控制：收缩压/舒张压<140/90 mmHg和<130/80 mmHg。高血压患病率为85.7%，98.9%的CRIC参与者知道这一诊断，98.3%的人接受了药物治疗，而高血压控制在<140/90 mmHg和<130/80 mmHg的比例分别为67.1%和46.1%。在患有高血压的 CRIC 参与者中，分别有 15%、25%、26% 和 32% 服用一种、两种、三种和四种或更多种抗高血压药物。经过多变量调整后，老年患者、黑人、尿白蛋白排泄量较高的患者将高血压控制在 <140/90 mmHg 和 <130/80 mmHg 的可能性较小，而服用 ACE 抑制剂和血管紧张素受体阻滞剂的参与者则更有可能将高血压控制在 <140/90 mmHg 和 <130/80 mmHg。数据来自单次研究访问。尽管这组 CKD 患者几乎普遍认识到高血压并接受治疗，但高血压控制率仍不理想。
A low rate of blood pressure control has been reported among patients with chronic kidney disease (CKD). These data were derived from population-based samples with a low rate of CKD awareness. Cross-sectional Data from the baseline visit of the Chronic Renal Insufficiency Cohort (CRIC) study (n=3612) were analyzed. Participants with an estimated glomerular filtration rate of 20 to 70 ml/min/1.73m2 were identified from physician offices and review of laboratory databases. Prevalence and awareness of hypertension, treatment patterns, control rates and factors associated with hypertension control. Following a standardized protocol, blood pressure was measured three times by trained staff and hypertension was defined as systolic blood pressure ≥140 mmHg and/or diastolic blood pressure ≥90 mmHg and/or self-reported antihypertensive medication use. Patients’ awareness and treatment of hypertension were defined using self-report and two levels of hypertension control were evaluated: systolic/diastolic blood pressure <140/90 mmHg and <130/80 mmHg. The prevalence of hypertension was 85.7%, and 98.9% of CRIC participants were aware of this diagnosis, 98.3% were treated with medications while 67.1% and 46.1% had their hypertension controlled to <140/90 mmHg and <130/80 mmHg, respectively. Of CRIC participants with hypertension, 15%, 25%, 26% and 32% were taking one, two, three and four or more antihypertensive medications, respectively. After multivariable adjustment, older patients, blacks, those with higher urinary albumin excretion were less likely while participants taking ACE-inhibitors and angiotensin receptor blockers were more likely to have controlled their hypertension to <140/90 mmHg and <130/80 mmHg. Data were derived from a single study visit. Despite almost universal hypertension awareness and treatment in this cohort of patients with CKD, rates of hypertension control were sub-optimal.
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影响因子：
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作者：
Coresh, J;Wei, L;Klag, MJ
通讯作者：
Klag, MJ
DOI：
10.1038/oby.2001.138
发表时间：
2001-11-01
期刊：
OBESITY RESEARCH
影响因子：
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作者：
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作者：
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Whelton, PK