Bowel-associated dermatosis-arthritis syndrome in a child with very early onset inflammatory bowel disease.

Bowel-associated dermatosis-arthritis syndrome in a child with very early onset inflammatory bowel disease.
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DOI:
10.1111/pde.14544
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发表时间:
2021-05
影响因子:
1.5
通讯作者:
Treat, James R.
Treat, James R.
中科院分区:
医学4区
文献类型:
--
作者:
Havele, Sonia A.;Clark, Ashley K.;Oboite, Michelle;Conrad, Maire A.;Perman, Marissa J.;Rubin, Adam I.;Treat, James R.

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一名患有严重极早发型炎症性肠病(VEO-IBD)的6岁男孩因高烧、稀便、关节痛和肌痛入院一周。随后,患者面部出现进行性丘疹和水疱脓疱性皮疹,并迅速扩散至躯干和四肢。组织学检查显示致密的真皮嗜酸性炎症。结果与肠道相关性皮肤病-关节炎综合征(BADAS)一致,这在儿童中很少报告,需要进一步表征。
A 6-year-old boy with severe very early-onset inflammatory bowel disease (VEO-IBD) was admitted for 1 week of high fevers, loose stools, joint pains, and myalgias. He subsequently developed a progressive, papular, and vesiculopustular eruption on his face with rapid spread to his trunk and extremities. Histopathology demonstrated dense dermal neutrophilic inflammation. Findings were consistent with bowel-associated dermatosis-arthritis syndrome (BADAS), which is rarely reported in children and requires further characterization.
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