Sleep protects memories from interference in older adults.
Sleep protects memories from interference in older adults.
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DOI：
10.1016/j.neurobiolaging.2015.03.010
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发表时间：
2015-07
影响因子：
4.2
通讯作者：
Spencer RMC
中科院分区：
文献类型：
--
作者：
Sonni A;Spencer RMC
在最近的一项研究中，我们证明了依赖睡眠的陈述性记忆巩固在老年人中得到了保留。本研究探讨了睡眠对老年人陈述性学习的益处是否反映了睡眠在保护记忆免受衰退方面的被动作用或在稳定记忆方面的积极作用。年轻人和老年人学习视觉空间任务，并在睡眠或清醒后进行回忆。虽然在睡眠和清醒后观察到性能降低，但在回忆之前与任务相关的干扰对清醒条件下的性能有更大的损害。这只适用于年轻人和表现出色的老年人。表现不佳的老年人在视觉空间任务中没有得到睡眠的好处。年轻人的表现变化与夜间NREM睡眠有关，而高表现老年人的表现变化与夜间REM睡眠有关。这些结果表明，由于主动记忆稳定过程，老年人的表现受益于睡眠;重要的是，睡眠的这种益处的程度与老年人最初获取情景信息的水平密切相关。
In a recent study, we demonstrated that sleep-dependent consolidation of declarative memories is preserved in older adults. The present study examined whether this benefit of sleep for declarative learning in older adults reflects a passive role of sleep in protecting memories from decay or an active role in stabilizing them. Young and older adults learned a visuo-spatial task and recall was probed following sleep or wake. Although a reduction in performance was observed following sleep and wake, task-related interference prior to recall had a larger detriment on performance in the wake condition. This was true for young and high performing older adults only. Low performing older adults did not receive a benefit of sleep on the visuo-spatial task. Performance changes were associated with early night NREM sleep in young adults and with early night REM sleep in high performing older adults. These results demonstrate that performance benefits from sleep in older adults as a result of an active memory stabilization process; importantly, the extent of this benefit of sleep is closely linked to the level of initial acquisition of the episodic information in older adults.
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DOI：
10.1891/1945-8959.10.2.167
发表时间：
2011-06-01
期刊：
Journal of cognitive education and psychology : JCEP
影响因子：
--
作者：
Donohue KC;Spencer RM
通讯作者：
Spencer RM
影响因子：
2.7
作者：
GIUDITTA, A;AMBROSINI, MV;VESCIA, S
通讯作者：
VESCIA, S
影响因子：
5.6
作者：
Buysse, DJ;Monk, TH;Begley, A
通讯作者：
Begley, A
影响因子：
2.1
作者：
Aly, Mariam;Moscovitch, Morris
通讯作者：
Moscovitch, Morris
影响因子：
2.8
作者：
Cajochen, C;Münch, M;Wirz-Justice, A
通讯作者：
Wirz-Justice, A