Cohort Profile Update: The British Regional Heart Study 1978-2018: 40 years of follow-up of older British men.

Cohort Profile Update: The British Regional Heart Study 1978-2018: 40 years of follow-up of older British men.
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DOI:
10.1093/ije/dyac122
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发表时间:
2023-06-06
影响因子:
7.7
通讯作者:
--
中科院分区:
医学1区
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--
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BRHS队列参与者在最初被招募到这项研究后,被邀请进行进一步的随访,金额为40美元。队列参与者完成了详细的邮寄问卷(2018年7月至12月)和体检(2018年8月至2019年1月),年龄为78-98岁。在研究开始时(1978-1980年),有7270名(94%)男性受雇(包括在军队中);而在2018年,在其余参与者中,3.8%(2010-12年为5.8%)报告称曾在有偿工作中度过任何时间。在晚年从工作过渡到退休或失业是一项重大挑战,包括但不限于经济不安全5、6和社会孤立,7这些问题的发生率随着年龄的增长而增加。与其他关于老年人的研究不同,8《家庭健康状况调查》清楚地捕捉到了从中年到高龄这段成人生命过程,并提供了与社区男性的社会、行为和生物因素有关的详细信息。9因此,这项研究相应地演变成侧重于与老年人更相关的问题。此外,自1978-1980年以来的客观和主观测量的纵向收集是一个丰富的数据集,可用于研究,以确定慢性病和死亡率的风险因素,并探索与健在队列中的健康老龄化有关的行为和社会因素(n?1633;图1)。对于缺席检查和问卷调查的参与者,可从全科医生记录和死亡率中获得健康信息。
BRHS cohort participants were invited for a further follow-up $40 years after their original recruitment into the study. The cohort participants completed a detailed postal questionnaire (July–December 2018) and a physical examination (August 2018–January 2019) when aged 78–98 years. At the beginning of the study (1978–80), 7270 (94%) men were employed (including being in the armed forces); whereas in 2018, of the remaining participants 3.8%(vs 5.8% at 2010–12) reported spending any time in paid work. Transitioning from work to retirement or unemployment in later life presents major challenges including, but not limited to, financial insecurity 5, 6 and social isolation, 7 which increase in prevalence with age. Unlike other studies of older old adults, 8 the BRHS has distinctively captured this period of the adult life course from middle age into very old ages, with detailed information related to social, behavioural and biological factors in community-dwelling men. 9 Thus, the Study has evolved accordingly to focus on issues that are more relevant to older adults. Furthermore, the longitudinal collection of objective and subjective measures since 1978–80 represents a rich dataset that is available for research to identify risk factors for chronic diseases and mortality and to explore behavioural and social factors related to healthy ageing among the surviving cohort (n ¼ 1633; Figure 1). For participants who are absent from the examination and questionnaire surveys, health information is available from GP records and mortality.
DOI: 10.1017/s0007114521000180
发表时间: 2021-07-14
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