Granulometric analysis of corneal endothelium specular images by using a germ-grain model

Granulometric analysis of corneal endothelium specular images by using a germ-grain model
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使用胚粒模型对角膜内皮镜面图像进行粒度分析

DOI:
10.1016/j.compbiomed.2006.04.005
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发表时间:
2007
影响因子:
7.7
通讯作者:
L. Martínez
L. Martínez
中科院分区:
工程技术2区
文献类型:
--
作者:
M. E. Díaz;G. Ayala;R. Sebastián;L. Martínez

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镜面显微镜被广泛应用于研究人角膜内皮在体内的状态。本文将角膜内皮用细胞内嵌圆组成的二值图像表示。该图像的补体的粒度分布函数被用作功能描述符,它提供了关于细胞的形状、大小和空间排列的信息。使用自举技术的实验评估显示其区分对照和病理病例的能力。它代表了一种可靠的图形替代经典指标(细胞密度、六边形和细胞面积变异系数),这些指标在检测细微异常时表现不佳。
Specular microscopy is widely used to study the human corneal endothelium status in vivo. In this paper, the corneal endothelium is represented as a binary image composed of the cell inscribed circles. The granulometric distribution function of the complement of this image is used as a functional descriptor, which provides information about the shape, size and spatial arrangement of cells. Experimental evaluation using bootstrap techniques shows its ability to discriminate between controls and pathological cases. It represents a reliable and graphical alternative to the classical indices (cell density, hexagonality and coefficient of variation of cell areas), which behave poorly when detecting subtle abnormalities.
DOI: 10.1001/archopht.1986.01050200070053
发表时间: 1986-08
影响因子: --
作者:
R. O. Schultz;D. Glasser;M. Matsuda;R. Yee;H. Edelhauser
通讯作者: R. O. Schultz;D. Glasser;M. Matsuda;R. Yee;H. Edelhauser
DOI: 10.3109/02713688509017661
发表时间: 1985-01-01
影响因子: 2
作者:
YEE, RW;MATSUDA, M;EDELHAUSER, HF
通讯作者: EDELHAUSER, HF
DOI: 10.1016/s0002-9394(14)72898-3
发表时间: 1994-08-01
影响因子: 4.2
作者:
BOURNE, WM;HODGE, DO;NELSON, LR
通讯作者: NELSON, LR