Patient preferences for lifestyle behaviours in osteoporotic fracture prevention: a cross-European discrete choice experiment.
Patient preferences for lifestyle behaviours in osteoporotic fracture prevention: a cross-European discrete choice experiment.
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骨质疏松性骨折预防中对生活方式行为的偏好：跨欧洲离散选择实验。
DOI：
10.1007/s00198-022-06310-4
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发表时间：
2022-06
期刊：
影响因子：
--
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中科院分区：
文献类型：
--
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通过离散选择实验，我们旨在评估患者在采用生活方式行为以预防骨质疏松性骨折方面的偏好。总体而言，从7个欧洲国家招募的1042名患者有利于一些生活方式行为(即进行适度的体力活动、服用钙和维生素D补充剂、减少饮酒和确保正常体重)。在药物治疗的同时，建议养成健康的生活方式来预防骨质疏松性骨折。在这项研究中，我们旨在评估患者在采取改变生活方式以预防骨质疏松性骨折方面的偏好。一项离散选择实验在七个欧洲国家进行。患有骨质疏松症或有骨质疏松症风险的患者被要求指出，他们将在多大程度上受到激励，坚持16种不同水平的6种属性的生活方式。建议的属性和水平是：体育活动(水平：不包括、中等或高水平)、钙和维生素D状况(水平：不包括、服用补充剂、改善营养并确保每天最低限度暴露在阳光下)、吸烟(水平：不包括、戒烟)、酒精(水平：不包括、适度摄入)、减肥(水平：不包括，确保健康体重)和预防跌倒(水平：不包括、接受一般建议或遵循一天的预防跌倒计划)。条件Logit模型被用来估计患者对所有参与者和每个国家的各种属性的相对偏好。总共有1042名患者完成了问卷调查。总体而言，患者倾向于采取预防骨质疏松性骨折的生活方式。然而，在所建议的生活方式行为中，患者一致认为不倾向于进行高水平的体力活动。此外，在爱尔兰、比利时、荷兰和瑞士，患者也不倾向于参加为期1天的预防跌倒计划，比利时、瑞士和荷兰的患者也不倾向于坚持均衡的营养计划。然而，我们在全球范围内观察到，患者对减少饮酒、进行适度的体力活动、服用钙和维生素D补充剂以及确保正常体重感到积极，所有这些措施都旨在预防骨折。在以患者为中心的方法中，骨折预防应考虑到这些考虑因素和偏好。网上版载有补充材料，可在10.1007/s00198-022-06310-4查阅。
Using a discrete choice experiment, we aimed to assess patients’ preferences with regard to adopting lifestyle behaviours to prevent osteoporotic fractures. Overall, the 1042 patients recruited from seven European countries were favourable to some lifestyle behaviours (i.e., engaging in moderate physical activity, taking calcium and vitamin D supplements, reducing their alcohol consumption and ensuring a normal body weight). Alongside medical therapy, healthy lifestyle habits are recommended for preventing osteoporotic fractures. In this study, we aimed to assess patients’ preferences with regard to adopting lifestyle changes to prevent osteoporotic fractures. A discrete choice experiment was conducted in seven European countries. Patients with or at risk of osteoporosis were asked to indicate to what extent they would be motivated to adhere to 16 lifestyle packages that differed in various levels of 6 attributes. The attributes and levels proposed were physical activity (levels: not included, moderate or high), calcium and vitamin D status (levels: not included, taking supplements, improving nutrition and assuring a minimal exposure to sunlight daily), smoking (levels: not included, quit smoking), alcohol (levels: not included, moderate consumption), weight reduction (levels: not included, ensure a healthy body weight) and fall prevention (levels: not included, receiving general advice or following a 1-day fall prevention program). A conditional logit model was used to estimate a patient’s relative preferences for the various attributes across all participants and per country. In total, 1042 patients completed the questionnaire. Overall, patients were favourable to lifestyle behaviours for preventing osteoporotic fractures. However, among the lifestyle behaviours proposed, patients were consensually not prone to engage in a high level of physical activity. In addition, in Ireland, Belgium, the Netherlands and Switzerland, patients were also not inclined to participate in a 1-day fall prevention program and Belgian, Swiss and Dutch patients were not prone to adhere to a well-balanced nutritional program. Nevertheless, we observed globally that patients felt positively about reducing their alcohol consumption, engaging in moderate physical activity, taking calcium and vitamin D supplements and ensuring a normal body weight, all measures aimed at preventing fractures. In a patient-centred approach, fracture prevention should take these considerations and preferences into account. The online version contains supplementary material available at 10.1007/s00198-022-06310-4.
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影响因子：
5.9
作者：
Giezenaar C;Chapman I;Luscombe-Marsh N;Feinle-Bisset C;Horowitz M;Soenen S
通讯作者：
Soenen S
影响因子：
4.2
作者：
Camacho, Pauline M.;Petak, Steven M.;Watts, Nelson B.
通讯作者：
Watts, Nelson B.
影响因子：
13.3
作者：
Buckley, Lenore;Guyatt, Gordon;McAlindon, Timothy
通讯作者：
McAlindon, Timothy
影响因子：
4.7
作者：
Horne, R;Weinman, J
通讯作者：
Weinman, J
影响因子：
4
作者：
Kanis, J. A.;Cooper, C.;Reginster, J. -Y.
通讯作者：
Reginster, J. -Y.