Executive function processes predict mobility outcomes in older adults.
Executive function processes predict mobility outcomes in older adults.
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DOI：
10.1111/jgs.12654
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发表时间：
2014-02
影响因子：
6.3
通讯作者：
McAuley E
中科院分区：
文献类型：
--
作者：
Gothe NP;Fanning J;Awick E;Chung D;Wójcicki TR;Olson EA;Mullen SP;Voss M;Erickson KI;Kramer AF;McAuley E
越来越多的证据表明，老年人的认知功能和身体表现之间存在联系。本研究通过一项为期12个月的随机对照运动试验，探讨了社区居住老年人执行功能指标与随后的活动结果之间的关系。随机对照临床试验Champaign-Urbana，Illinois社区居住的老年人（N = 179;法师= 66.4）一项为期12个月的锻炼试验，包括两个手臂：有氧运动组和拉伸和强化组。建立了执行功能的认知测试，包括侧翼任务、任务转换和双重任务范式，以及威斯康星州卡片分类测试。使用定时的8英尺上升和行走测试以及爬上和爬下楼梯的时间来评估移动性。参与者在基线时完成认知测量，在基线时和干预12个月后完成活动测量。进行多元回归分析，以确定是否基线执行功能预测干预后的功能表现后，控制年龄，性别，教育，心肺功能和基线活动水平。我们的分析显示，选择性基线执行功能测量，特别是侧翼任务（β = 0.15至0.17）和威斯康星州卡片分类测试（β = 0.11至0.16）的表现，一致预测12个月时的活动结果。估计值在预期的方向上，因此执行功能测量的基线表现越好，独立于干预组的定时移动性测试的表现越好。执行功能中的抑制控制、心理定势转换和注意灵活性对功能移动性有预测作用。鉴于文献中将活动受限与残疾、发病率和死亡率联系起来，这些结果对于理解活动功能不良的前因非常重要，而活动功能不良可以通过精心设计的干预措施来减轻，以改善认知能力。
There is growing evidence suggesting an association between cognitive function and physical performance in late life. This study examined the relationship between performance on executive function measures and subsequent mobility outcomes among community dwelling older adults across a 12-month randomized controlled exercise trial. Randomized controlled clinical trial Champaign-Urbana, Illinois Community dwelling older adults (N = 179; Mage = 66.4) A 12-month exercise trial with two arms: an aerobic exercise group and a stretching and strengthening group Established cognitive tests of executive function including the flanker task, task switching and a dual task paradigm, and the Wisconsin card sort test. Mobility was assessed using the timed 8-foot up and go test and times to climb up and down a flight of stairs. Participants completed the cognitive measures at baseline and the mobility measures at baseline and after 12 months of the intervention. Multiple regression analyses were conducted to determine whether baseline executive function predicted post-intervention functional performance after controlling for age, sex, education, cardiorespiratory fitness and baseline mobility levels. Our analyses revealed that selective baseline executive function measures, particularly performance on the flanker task (β’s =.15 to .17) and the Wisconsin card sort test (β’s =.11 to .16) consistently predicted mobility outcomes at month 12. The estimates were in the expected direction, such that better baseline performance on the executive function measures predicted better performance on the timed mobility tests independent of the intervention group. Executive functions of inhibitory control, mental set shifting and attentional flexibility were predictive of functional mobility. Given the literature associating mobility limitations with disability, morbidity, and mortality, these results are important for understanding the antecedents to poor mobility function that can be attenuated by well-designed interventions to improve cognitive performance.
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影响因子：
3.5
作者：
Erickson, Kirk I.;Prakash, Ruchika S.;Voss, Michelle W.;Chaddock, Laura;Hu, Liang;Morris, Katherine S.;White, Siobhan M.;Wojcicki, Thomas R.;McAuley, Edward;Kramer, Arthur F.
通讯作者：
Kramer, Arthur F.
影响因子：
5.5
作者：
McAuley, Edward;Mullen, Sean P.;Kramer, Arthur F.
通讯作者：
Kramer, Arthur F.
DOI：
10.1093/gerona/62.11.1244
发表时间：
2007-11-01
影响因子：
5.1
作者：
Fitzpatrick, Annette L.;Buchanan, Catherine K.;Williamson, Jeff D.
通讯作者：
Williamson, Jeff D.
影响因子：
4.7
作者：
McAuley, Edward;Szabo, Amanda N;Kramer, Arthur F
通讯作者：
Kramer, Arthur F
影响因子：
9.9
作者：
O'Sullivan, M;Jones, DK;Markus, HS
通讯作者：
Markus, HS