Chemotactic behavior of myoblasts.

Chemotactic behavior of myoblasts.
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成肌细胞的趋化行为。

DOI:
10.1016/0012-1606(84)90098-8
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发表时间:
1984
影响因子:
2.7
通讯作者:
Solursh,M
Solursh,M
中科院分区:
生物学3区
文献类型:
--
作者:
Venkatasubramanian,K;Solursh,M

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早期的研究表明体节起源的肌源性细胞迁移到发育肢体,但对影响迁移模式的因素知之甚少。为了了解肌原性细胞的迁移行为,使用改良的Boyden室测定系统测试胚胎骨骼肌细胞的趋化迁移能力。这是第一次,胚胎骨骼肌细胞有能力向血小板衍生生长因子(PDGF)和PDGF样因子存在于血清和鸡胚提取物(CEE)的梯度迁移。另一方面,非肌源性肢体间充质细胞不表现出这样的反应。在此提出一个假设,即来自已经形成图案的脉管系统的趋化因子可能会影响早期肢体发育过程中骨骼肌细胞的分布。
Earlier studies have suggested that myogenic cells of somite origin migrate into the developing limb, but little is known about the factors affecting the pattern of migration. In order to understand the migratory behavior of myogenic cells, embryonic skeletal muscle cells were tested for their ability to migrate chemotactically using a modified Boyden chamber assay system. It is shown here, for the first time, that embryonic skeletal muscle cells have the capacity to migrate toward a gradient of platelet-derived growth factor (PDGF) and PDGF-like factors present in serum and chick embryo extract (CEE). On the other hand, nonmyogenic limb mesenchyme cells do not exhibit such a response. A hypothesis is proposed here that chemotactic factors from the already patterned vasculature might influence the distribution of skeletal muscle cells during early limb development.
人血小板生长因子对人胎儿和成人二倍体成纤维细胞生长和形态的比较影响。
DOI: --
发表时间: 1977
影响因子: 3.7
作者:
J. Slayback;L. Cheung;R. Geyer
通讯作者: R. Geyer
DOI: --
发表时间: 1977
期刊: The Journal of experimental zoology
影响因子: --
作者:
P. Ahrens;M. Solursh;S. Meier
通讯作者: S. Meier
DOI: 10.1016/0012-1606(83)90063-5
发表时间: 1983-05
影响因子: 2.7
作者:
B. Swalla;E. M. Owens;T. Linsenmayer;Michael Solursh
通讯作者: B. Swalla;E. M. Owens;T. Linsenmayer;Michael Solursh
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DOI: --
发表时间: 1982
影响因子: 4.8
作者:
R. Ehrismann;D. E. Roth;H. Eppenberger;D. Turner
通讯作者: D. Turner
DOI: 10.1126/science.493992
发表时间: 1979-01-01
期刊: SCIENCE
影响因子: 56.9
作者:
GUNDERSEN, RW;BARRETT, JN
通讯作者: BARRETT, JN