Fit and Strong! Plus: Twelve and eighteen month follow-up results for a comparative effectiveness trial among overweight/obese older adults with osteoarthritis.

Fit and Strong! Plus: Twelve and eighteen month follow-up results for a comparative effectiveness trial among overweight/obese older adults with osteoarthritis.
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DOI:
10.1016/j.ypmed.2020.106267
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发表时间:
2020-12
影响因子:
5.1
通讯作者:
Hughes SL
Hughes SL
中科院分区:
医学2区
文献类型:
--
作者:
Fitzgibbon ML;Tussing-Humphreys L;Schiffer L;Smith-Ray R;Marquez DX;DeMott AD;Berbaum ML;Hughes SL

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This comparative effectiveness trial compared the longer-term effectiveness (12 and 18 months) of the standard Fit & Strong! physical activity program to Fit & Strong! Plus, which combined physical activity and dietary weight loss. Outcomes were weight, diet quality, physical activity, osteoarthritis symptoms, performance measures, and anxiety/depression. In this study, 413 overweight/obese participants with OA, ≥60 years old and primarily African American, were randomly assigned to Fit & Strong! (F&S!) or Fit & Strong! Plus (F&S! Plus), with outcomes assessed at 2, 6, 12, and 18 months. 356 (86%) participants completed the 18-month visit. Compared with participants randomized to standard F&S!, F&S! Plus participants maintained longer-term benefits at 12 months in weight (mean change ± SE: −1.7 ± 0.3 kg for F&S! Plus vs −0.9 ± 0.3 kg for F&S!, p = 0.049), BMI (−0.6 ± 0.1 vs −0.3 ± 0.1 kg/m2, p = 0.04), waist circumference (−2.7 ± 0.6 vs −0.4 ± 0.6 cm, p = 0.004), and lower extremity strength (1.6 ± 0.2 vs 1.0 ± 0.2 chair stands, p = 0.046). At 18 months, F&S! Plus participants showed improved lower extremity strength (1.4 ± 0.2 vs. 0.7 ± 0.2 chair stands, p = 0.045. African American older adults in the F&S! Plus arm showed sustained modest improvements in weight, waist circumference, and lower extremity strength at 12 months and in lower extremity strength at 18 months compared to F&S!. Implications for the translation of evidence-based programs into community settings to support healthy behaviors in older adults are discussed.
DOI: 10.1038/oby.2009.175
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