An update on canine coronaviruses: viral evolution and pathobiology.
An update on canine coronaviruses: viral evolution and pathobiology.
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DOI：
10.1016/j.vetmic.2008.06.007
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发表时间：
2008-12-10
影响因子：
3.3
通讯作者：
Buonavoglia C
中科院分区：
文献类型：
--
作者：
Decaro N;Buonavoglia C
人类严重急性呼吸综合征的出现重新激发了人们对动物冠状病毒(CoV)作为直接和间接人畜共患病潜在病原体的兴趣。加强了对冠状病毒的流行病学监测，从而在动物和人类中发现了新的病毒、基因类型、致病类型和宿主变异。在狗身上，一种与轻度肠炎有关的冠状病毒--犬冠状病毒(CCoV)--自20世纪70年代以来就已被发现。最近几年，在犬身上发现了与经典冠状病毒不同的生物学和遗传学特性的冠状病毒毒株，这导致了对冠状病毒引起的犬病的全面重新考虑。犬冠状病毒的遗传进化是冠状病毒如何通过积累病毒基因组中的点突变、插入或缺失而进化的典范，这导致了新的基因类型(冠状病毒I型)、生物型(泛嗜性冠状病毒)和宿主变异(犬呼吸道冠状病毒)。本文就近年来冠状病毒的遗传进化和新冠状病毒在犬体内的出现作一综述。文中还讨论了新获得的信息对犬的健康状况和预防规划的意义。
The emergence of human severe acute respiratory syndrome incited renewed interest in animal coronaviruses (CoVs) as potential agents of direct and indirect zoonoses. The reinforced epidemiological surveillance on CoVs has led to the identification of new viruses, genotypes, pathotypes and host variants in animals and humans. In dogs, a CoV associated with mild enteritis, canine coronavirus (CCoV), has been known since 1970s. CoV strains with different biological and genetic properties with respect to classical CCoV strains have been identified in dogs in the last few years, leading to a full reconsideration of the CoV-induced canine diseases. The genetic evolution of dog CoVs is paradigmatic of how CoVs evolve through accumulation of point mutations, insertions or deletions in the viral genome, that led to the emergence of new genotypes (CCoV type I), biotypes (pantropic CCoV) and host variants (canine respiratory coronavirus). This paper is a review of the current literature on the recent genetic evolution of CCoV and emergence of new CoVs in the dog. The significances of the newly acquired information for the canine health status and prophylaxis programmes are also discussed.
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影响因子：
3.1
作者：
Decaro N;Martella V;Ricci D;Elia G;Desario C;Campolo M;Cavaliere N;Di Trani L;Tempesta M;Buonavoglia C
通讯作者：
Buonavoglia C
影响因子：
2.2
作者：
Benetka, V.;Kolodziejek, J.;Moestl, K.
通讯作者：
Moestl, K.
影响因子：
2.7
作者：
Erles, K;Brownlie, J
通讯作者：
Brownlie, J
影响因子：
3.1
作者：
Decaro N;Pratelli A;Campolo M;Elia G;Martella V;Tempesta M;Buonavoglia C
通讯作者：
Buonavoglia C
犬的犬冠状病毒高度致病性。
影响因子：
11.8
作者：
Buonavoglia C;Decaro N;Martella V;Elia G;Campolo M;Desario C;Castagnaro M;Tempesta M
通讯作者：
Tempesta M