Grafts of porcine small intestinal submucosa seeded with cultured homologous smooth muscle cells for bladder repair in dogs.
Grafts of porcine small intestinal submucosa seeded with cultured homologous smooth muscle cells for bladder repair in dogs.
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DOI：
10.1186/1751-0147-55-39
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发表时间：
2013-05-07
影响因子：
2.1
通讯作者：
Brandão CV
中科院分区：
文献类型：
--
作者：
Rossetto VJ;da Mota LS;Rocha NS;Miot HA;Grandi F;Brandão CV
由于胃肠道扩大膀胱成形术存在许多并发症，本研究旨在分析猪小肠粘膜下层（SIS）移植物与培养的同种平滑肌细胞一起用于10只雌性犬膀胱的解剖修复，并与脱细胞SIS移植物进行比较。我们通过临床检查、腹部超声和实验室检查评估了每种类型移植物可能的副作用和并发症。新形成的膀胱的解剖修复进行了评估H/E和Masson的三色组织学染色，分析与尼康显微镜连接到系统的图像分析图像J。我们建议，SIS相关的同源平滑细胞可以提高组织修复的质量，从而减少潜在的并发症固有的脱细胞SIS。
Due to numerous complications associated to gastrointestinal augmented cystoplasty, this study aimed to analyze the anatomic repair of the bladder of 10 female dogs using grafts of porcine small intestinal submucosa (SIS) seeded with cultured homologous smooth muscle cells, and compare them with the acellular SIS grafts. We assessed the possible side effects and complications of each type of graft by clinical examination, abdominal ultrasound and laboratory findings. Anatomic repair of neoformed bladder was assessed by histological staining for H/E and Masson's Trichrome, analyzed with a Nikon Photomicroscope connected to the system of image analysis Image J. We propose that SIS associated to homologous smooth cells can improve the quality of tissue repair, and consequently decrease the potential complications inherent to acellular SIS.
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影响因子：
6.6
作者：
Gitlin, JS;Wu, XR;Shapiro, E
通讯作者：
Shapiro, E
影响因子：
2.7
作者：
Kropp, BP;Cheng, EY
通讯作者：
Cheng, EY
影响因子：
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作者：
Rigaud, J;Le Normand, L
通讯作者：
Le Normand, L
影响因子：
4.5
作者：
Kimuli, M;Eardley, I;Southgate, J
通讯作者：
Southgate, J
影响因子：
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作者：
Zhang, YY;Lin, HK;Kropp, BP
通讯作者：
Kropp, BP