Some principles of organization of spinal neurons underlying locomotion in zebrafish and their implications.

Some principles of organization of spinal neurons underlying locomotion in zebrafish and their implications.
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斑马鱼运动及其含义的脊柱神经元组织的一些原则。

DOI:
10.1111/j.1749-6632.2010.05539.x
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发表时间:
2010-06
影响因子:
5.2
通讯作者:
McLean DL
McLean DL
中科院分区:
综合性期刊3区
文献类型:
--
作者:
Fetcho JR;McLean DL

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最近对斑马鱼脊柱运动系统的研究,以及对其他物种的研究,揭示了脊髓运动网络组织和募集的一些原理:(1)由一系列转录因子、关键形态特征和递质表型定义的广泛神经元类别,有序地从脊髓的不同背腹区出现;(2)运动行为、运动神经元和中间神经元按顺序区分,从一般的、通常较快的运动和驱动它们的神经元到逐渐较慢的运动及其底层神经元;(3)运动神经元和中间神经元的募集顺序以分化时间为基础;(4)不同的运动速度涉及活跃的中间神经元组的一定移位。在这里,我们回顾一下这些原理,以及它们对大脑其他部分、其他脊椎动物和肢体运动的一些启示。
Recent studies of the spinal motor system of zebrafish, along with work in other species, are leading to some principles that appear to underlie the organization and recruitment of motor networks in cord: (1) broad neuronal classes defined by a set of transcription factors, key morphological features, and transmitter phenotypes arise in an orderly way from different dorso-ventral zones in spinal cord; (2) motor behaviors and both motoneurons and interneurons differentiate in order from gross, often faster, movements and the neurons driving them to progressively slower movements and their underlying neurons; (3) recruitment order of motoneurons and interneurons is based upon time of differentiation; (4) different locomotor speeds involve some shifts in the set of active interneurons. Here we review these principles and some of their implications for other parts of the brain, other vertebrates, and limbed locomotion.
DOI: 10.1002/cne.901940411
发表时间: 1980-01-01
影响因子: 2.5
作者:
ALTMAN, J;BAYER, SA
通讯作者: BAYER, SA
DOI: 10.1038/nature02518
发表时间: 2004-06-03
期刊: NATURE
影响因子: 64.8
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DOI: 10.1002/cne.902990303
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影响因子: 2.5
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DOI: 10.1113/jphysiol.1984.sp015511
发表时间: 1984-01-01
影响因子: 5.5
作者:
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