Preference for concentric orientations in the mouse superior colliculus.

Preference for concentric orientations in the mouse superior colliculus.
复制标题

偏爱小鼠上丘的同心方向。

DOI:
10.1038/ncomms7773
复制
发表时间:
2015-04-02
影响因子:
16.6
通讯作者:
Heimel, J. Alexander
Heimel, J. Alexander
中科院分区:
综合性期刊1区
文献类型:
--
作者:
Ahmadlou, Mehran;Heimel, J. Alexander

文献摘要

参考文献

被引文献

相似文献

上丘是一种分层结构,对身体和凝视的反应很重要。其浅层是仅次于外侧膝状核的视网膜神经节轴突的第二个主要靶点,是视网膜组织的。在这里,我们展示了在老鼠身上,也有一个精确的定向偏好组织。在垂直于顶盖表面的柱中,神经元对相同的视觉位置作出反应,并偏爱相同方向的栅格。钙离子成像和细胞外记录显示,首选的光栅随着视网膜位置的不同而不同,并平行于通过感受野围绕视觉中心的同心圆。这意味着并不是所有的方向在整个视野中都被同等地表示。这使得上丘不同于视觉皮质,不适合于平移不变的物体识别,并表明视觉刺激可能会根据其视网膜位置的不同而产生不同的行为后果。哺乳动物上丘(SC)处理视觉刺激,但对特定视觉特征反应偏好的空间组织知之甚少。在这里,作者表明,鼠标SC包含一个方向偏好图,使得首选的光栅方向与视野中心周围的同心圆对齐。
The superior colliculus is a layered structure important for body- and gaze-orienting responses. Its superficial layer is, next to the lateral geniculate nucleus, the second major target of retinal ganglion axons and is retinotopically organized. Here we show that in the mouse there is also a precise organization of orientation preference. In columns perpendicular to the tectal surface, neurons respond to the same visual location and prefer gratings of the same orientation. Calcium imaging and extracellular recording revealed that the preferred grating varies with retinotopic location, and is oriented parallel to the concentric circle around the centre of vision through the receptive field. This implies that not all orientations are equally represented across the visual field. This makes the superior colliculus different from visual cortex and unsuitable for translation-invariant object recognition and suggests that visual stimuli might have different behavioural consequences depending on their retinotopic location. The mammalian superior colliculus (SC) processes visual stimuli but little is known about the spatial organization of the response preferences for specific visual features. Here the authors show that the mouse SC contains a map for orientation preference such that preferred grating orientation is aligned to concentric circles around the centre of the visual field.
DOI: 10.1523/jneurosci.0907-11.2011
发表时间: 2011-05-25
期刊: The Journal of neuroscience : the official journal of the Society for Neuroscience
影响因子: --
作者:
Kay JN;De la Huerta I;Kim IJ;Zhang Y;Yamagata M;Chu MW;Meister M;Sanes JR
通讯作者: Sanes JR
DOI: 10.1007/bf00248906
发表时间: 1989-01-01
影响因子: 2
作者:
BAUER, R;DOW, BM
通讯作者: DOW, BM
DOI: 10.1038/321579a0
发表时间: 1986-06-05
期刊: NATURE
影响因子: 64.8
作者:
BLASDEL, GG;SALAMA, G
通讯作者: SALAMA, G
DOI: 10.1038/253203a0
发表时间: 1975-01-01
期刊: NATURE
影响因子: 64.8
作者:
DRAGER, UC;HUBEL, DH
通讯作者: HUBEL, DH
DOI: 10.1152/jn.00059.2007
发表时间: 2007-07-01
影响因子: 2.5
作者:
Girman, S. V.;Lund, R. D.
通讯作者: Lund, R. D.