Gene expression atlas at the European bioinformatics institute.

Gene expression atlas at the European bioinformatics institute.
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DOI:
10.1093/nar/gkp936
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发表时间:
2010-01
影响因子:
14.9
通讯作者:
Brazma A
Brazma A
中科院分区:
生物学2区
文献类型:
--
作者:
Kapushesky M;Emam I;Holloway E;Kurnosov P;Zorin A;Malone J;Rustici G;Williams E;Parkinson H;Brazma A

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基因表达图谱(http://www.ebi.ac.uk/gxa)是一个增值数据库,提供有关不同细胞类型、生物体部位、发育阶段、疾病状态、样本处理和其他生物/实验条件中基因表达的信息。该数据库的内容来源于对ArrayExpress功能基因组学数据档案中选定数据的策展、重新注释和统计分析。一个简单的界面允许用户查询差异基因表达,或者(i)通过基因名称或属性,如基因本体论术语,或(ii)通过生物条件,如疾病,生物体部分或细胞类型。基因查询返回已报告表达的条件,而条件查询返回在这些条件下报告表达的基因。两种查询类型的组合是可能的。查询结果使用各种统计措施进行排名,并通过数据库中有多少独立研究显示特定的基因-条件关联。目前,该数据库包含来自9个物种的20多万个基因的信息,以及来自1000多项独立研究的30 000多项检测中研究的近4500种生物条件。
The Gene Expression Atlas (http://www.ebi.ac.uk/gxa) is an added-value database providing information about gene expression in different cell types, organism parts, developmental stages, disease states, sample treatments and other biological/experimental conditions. The content of this database derives from curation, re-annotation and statistical analysis of selected data from the ArrayExpress Archive of Functional Genomics Data. A simple interface allows the user to query for differential gene expression either (i) by gene names or attributes such as Gene Ontology terms, or (ii) by biological conditions, e.g. diseases, organism parts or cell types. The gene queries return the conditions where expression has been reported, while condition queries return which genes are reported to be expressed in these conditions. A combination of both query types is possible. The query results are ranked using various statistical measures and by how many independent studies in the database show the particular gene-condition association. Currently, the database contains information about more than 200 000 genes from nine species and almost 4500 biological conditions studied in over 30 000 assays from over 1000 independent studies.
DOI: 10.1093/nar/gkn664
发表时间: 2009-01
影响因子: 14.9
作者:
UniProt Consortium
通讯作者: UniProt Consortium
DOI: 10.1093/nar/gkn764
发表时间: 2009-01
影响因子: 14.9
作者:
Barrett T;Troup DB;Wilhite SE;Ledoux P;Rudnev D;Evangelista C;Kim IF;Soboleva A;Tomashevsky M;Marshall KA;Phillippy KH;Sherman PM;Muertter RN;Edgar R
通讯作者: Edgar R
DOI: 10.1093/nar/gkn889
发表时间: 2009-01
影响因子: 14.9
作者:
Parkinson H;Kapushesky M;Kolesnikov N;Rustici G;Shojatalab M;Abeygunawardena N;Berube H;Dylag M;Emam I;Farne A;Holloway E;Lukk M;Malone J;Mani R;Pilicheva E;Rayner TF;Rezwan F;Sharma A;Williams E;Bradley XZ;Adamusiak T;Brandizi M;Burdett T;Coulson R;Krestyaninova M;Kurnosov P;Maguire E;Neogi SG;Rocca-Serra P;Sansone SA;Sklyar N;Zhao M;Sarkans U;Brazma A
通讯作者: Brazma A
DOI: 10.1111/j.2517-6161.1995.tb02031.x
发表时间: 1995-01-01
影响因子: 5.8
作者:
BENJAMINI, Y;HOCHBERG, Y
通讯作者: HOCHBERG, Y
DOI: 10.1073/pnas.012025199
发表时间: 2002-04-02
影响因子: 11.1
作者:
Su, AI;Cooke, MP;Hogenesch, JB
通讯作者: Hogenesch, JB