Fabrication of functional magnetic cellulose nanocomposite membranes for controlled adsorption of protein
Fabrication of functional magnetic cellulose nanocomposite membranes for controlled adsorption of protein
复制标题
用于控制蛋白质吸附的功能性磁性纤维素纳米复合膜的制备
DOI：
10.1007/s10570-018-1750-2
复制
发表时间：
2018-03
期刊：
影响因子：
5.7
通讯作者：
Jianguo Wang
中科院分区：
文献类型：
--
作者：
Hao Wu;Chao Teng;Yanru Li;Huafeng Tian;Jianguo Wang
制备了具有预定功能的纤维素纳米复合膜，并将其作为蛋白质吸附剂进行了评价。分别用甘氨酸和柠檬酸钠对磁赤铁矿纳米粒子进行修饰，得到了带有氨基和羧基的磁赤铁矿纳米粒子。然后将功能性磁赤铁矿纳米颗粒分散到NaOH/尿素水溶液中溶解纤维素，并使用流延法构建磁性膜。通过zeta电位和FTIR测试对改性后的MNP进行了表征。纤维素纳米复合膜具有微孔结构，孔隙率大于88.3%。在pH = 4时，带有羧基的MNP对蛋白质的吸附量最大，随着pH从4增加到6，吸附量逐渐降低。然而，纤维素纳米复合膜与引入的MNP与氨基吸收的最高和最低量的蛋白质在pH值为5和4，分别。该研究为设计用于蛋白质吸附的多功能纤维素纳米复合膜提供了一种绿色、简便的方法，并有望通过选择不同的纳米填料和介质pH值为生物分子结合开辟新的途径。
Cellulose nanocomposite membranes with predesigned functions were prepared and evaluated as adsorbents for protein adsorption. Maghemite nanoparticles (MNP) with amino groups and carboxyl groups were obtained by modifying maghemite nanoparticles with glycine and sodium citrate, respectively. The functional maghemite nanoparticles were then dispersed into NaOH/urea aqueous solution for dissolving cellulose, and the magnetic membranes were constructed using a tape casting method. The modified MNP were evaluated by zeta potential and FTIR measurements. The developed cellulose nanocomposite membranes possess microporous structure with porosity higher than 88.3%. The introduction of MNP with carboxyl groups into the cellulose nanocomposite membranes could absorb the highest amount of protein at a pH of 4, and gradually decreased with the increase of pH from 4 to 6. However, cellulose nanocomposite membranes with introduced MNP with amino groups absorb the highest and lowest amount of protein at pH of 5 and 4, respectively. This study provides a green and simple method for the design of multifunctional cellulose nanocomposite membranes for controllable protein adsorption, and is expected to open new venues for biomolecule binding by choice of various nanofillers and pH of the medium.
登录
查看更多内容
影响因子：
11.2
作者：
Xiaogang Luo;Hao Zhang;Zhenni Cao;Ning Cai;Yanan Xue;Faquan Yu
通讯作者：
Xiaogang Luo;Hao Zhang;Zhenni Cao;Ning Cai;Yanan Xue;Faquan Yu
影响因子：
9.9
作者：
Abedini, Reza;Mousavi, Seyed Mahmoud;Aminzadeh, Reza
通讯作者：
Aminzadeh, Reza
DOI：
10.1016/j.msec.2017.05.019
发表时间：
2017-10
期刊：
Materials science & engineering. C, Materials for biological applications
影响因子：
--
作者：
Hao Zhang;Xiaogang Luo;Hu Tang;Mingming Zheng;Fenghong Huang
通讯作者：
Hao Zhang;Xiaogang Luo;Hu Tang;Mingming Zheng;Fenghong Huang
影响因子：
12.8
作者：
A. Siddiqui;S. Lehmann;V. Haaksman;J. Ogier;C. Schellenberg;M. Loosdrecht;J. Kruithof;J. Vrouwenvelder;J. Vrouwenvelder
通讯作者：
A. Siddiqui;S. Lehmann;V. Haaksman;J. Ogier;C. Schellenberg;M. Loosdrecht;J. Kruithof;J. Vrouwenvelder;J. Vrouwenvelder
影响因子：
3.2
作者：
A. El-Hag Ali;N. El-Sawy;E. Hegazy;Ahmed Awadallah‐F
通讯作者：
A. El-Hag Ali;N. El-Sawy;E. Hegazy;Ahmed Awadallah‐F