Histologic Lung Cancer Incidence Rates and Trends Vary by Race/Ethnicity and Residential County.
Histologic Lung Cancer Incidence Rates and Trends Vary by Race/Ethnicity and Residential County.
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DOI：
10.1016/j.jtho.2017.12.010
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发表时间：
2018-04
期刊：
影响因子：
--
通讯作者：
Ryan BM
中科院分区：
文献类型：
--
作者：
Houston KA;Mitchell KA;King J;White A;Ryan BM
在美国，NH黑人的肺癌发病率高于NH白色和西班牙裔人群。然而，国家癌症估计可能并不总是反映小地理区域的差异和发病率方面的癌症负担，特别是城乡差异。此外，文献中关于癌症组织学方面的城乡差异存在差距。使用基于人群的癌症登记数据-监测、流行病学和最终结果（SEER）和国家癌症登记计划（NPCR）-我们按种族/民族和首次癌症诊断时的居住县位置呈现年龄调整的组织学率和趋势。计算比率以检查比率的种族/民族差异。计算年度百分比变化（APC），以测量随时间推移的速率变化。我们发现，鳞状细胞癌（SCC）的下降发生在大都市县最快，而腺癌的比例增加最快的县不毗邻大都市地区。此外，虽然NH黑人男性肺癌发病率增加NH白色和西班牙裔男性在所有地理位置相比，我们发现，随着居住的农村化程度的增加，差距的程度增加。最后，我们报告，在小于55岁的妇女诊断，SCC和腺癌的发病率较高的NH黑人相比，NH白人。我们的研究结果突出了非相邻农村地区NH黑人之间的差异。这些发现可能对戒烟和肺癌筛查计划的实施产生重大影响。
Lung cancer incidence is higher among NH blacks compared with NH white and Hispanic populations in the U.S. However, national cancer estimates may not always reflect the cancer burden in terms of disparities and incidence in small geographic areas, especially urban-rural disparities. Moreover, there is a gap in the literature regarding rural-urban disparities in terms of cancer histology. Using population-based cancer registry data—Surveillance, Epidemiology and End Results (SEER) and National Program of Cancer Registries (NPCR)—we present age-adjusted histologic rates and trends by race/ethnicity, and residential county location at the time of first cancer diagnosis. Rate ratios were calculated to examine racial/ethnic differences in rates. Annual percent change (APC) was calculated to measure changes in rates over time. We find that declines in squamous cell carcinoma (SCC) are occurring fastest in metropolitan counties, while rates of adenocarcinoma increased fastest in counties nonadjacent to metropolitan areas. Further, while NH black men have increased lung cancer incidence compared with NH white and Hispanic men in all geographic locations, we find that the degree of the disparity increases with increasing rurality of residence. Finally, we report that among women diagnosed at less than 55 years of age, the incidence of SCC and adenocarcinoma was higher for NH blacks compared with NH whites. Our results highlight disparities among NH blacks in non-adjacent rural areas. These findings may have significant impact for the implementation of smoking cessation and lung cancer screening programs.
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DOI：
10.1158/1055-9965.epi-17-0092
发表时间：
2017-07
期刊：
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
影响因子：
--
作者：
Blake KD;Moss JL;Gaysynsky A;Srinivasan S;Croyle RT
通讯作者：
Croyle RT
影响因子：
5.6
作者：
Carpenter, CL;Jarvik, ME;London, SJ
通讯作者：
London, SJ
影响因子：
6.3
作者：
AXELSON, O;ANDERSSON, K;WINGREN, G
通讯作者：
WINGREN, G
影响因子：
2.3
作者：
Blake, Barbara J.;Taylor, Gloria A. Jones;Sowell, Richard L.
通讯作者：
Sowell, Richard L.
影响因子：
3.4
作者：
Curtin, Geoffrey M.;Sulsky, Sandra I.;Swauger, James E.
通讯作者：
Swauger, James E.