Epithelioid trophoblastic tumor of the uterus: Cytological and immunohistochemical observation of a case
Epithelioid trophoblastic tumor of the uterus: Cytological and immunohistochemical observation of a case
复制标题
子宫上皮样滋养细胞肿瘤1例细胞学及免疫组化观察
DOI：
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发表时间：
2002
期刊：
影响因子：
--
通讯作者：
T. Araki
中科院分区：
文献类型：
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作者：
S. Kamoi;Y. Ohaki;O. Mori;M. Yokoyama;Y. Kawamoto;T. Kawamura;T. Araki
上皮样滋养细胞肿瘤（Epithelioid trophoblastic tumor，ETT）是一种新的滋养细胞肿瘤。然而，仅报告了3例支持ETT的后续病例。最近，我们在一名37岁女性中经历了一例ETT，其术前子宫内膜刷检显示非典型单核巨细胞，并因诊断为子宫肌瘤而接受子宫切除术。标本显示位于子宫下段的2.5 × 3.0 cm黄褐色壁内结节，由上皮样排列的中间滋养细胞的肿瘤性增生组成。免疫组织化学显示，肿瘤细胞呈细胞角蛋白和α-谷氨酰胺蛋白弥漫阳性，人绒毛膜促性腺激素和人胎盘催乳素局灶阳性。截至2001年9月，她提出了一个平静的临床过程。
Epithelioid trophoblastic tumor (ETT) is a new entity of trophoblastic tumor and 14 such cases were reported by Shih and Kurman in 1998. However, only three subsequent cases supporting ETT have been reported. Recently, we experienced a case of ETT in a 37‐year‐old woman whose preoperative endometrial brushings showed atypical mononucleate giant cells and who underwent hysterectomy with the diagnosis of a uterine fibroid. The specimens revealed a 2.5 × 3.0 cm yellow–tan intramural nodule located in the lower uterine segment, which was composed of a neoplastic proliferation of intermediate trophoblasts in epithelioid arrangements. Immunohistochemically, the tumor cells were diffusely positive for cytokeratin and inhibin‐α, and focally positive for human chorionic gonadotropin and human placental lactogen. She presented an uneventful clinical course as of September 2001.
影响因子：
3.8
作者：
KURMAN, RJ;MAIN, CS;CHEN, HC
通讯作者：
CHEN, HC
胎盘催乳素和绒毛膜促性腺激素在正常胎盘和滋养层肿瘤中的免疫细胞化学定位，重点是中间滋养层和胎盘部位滋养层肿瘤。
DOI：
10.1097/00004347-198403010-00009
发表时间：
1984
期刊：
International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists
影响因子：
--
作者：
Kurman,RJ;Young,RH;Norris,HJ;Main,CS;Lawrence,WD;Scully,RE
通讯作者：
Scully,RE