Factors affecting health-related quality of life in older patients with chronic kidney disease: a single-center cross-sectional study

Factors affecting health-related quality of life in older patients with chronic kidney disease: a single-center cross-sectional study
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影响老年慢性肾病患者健康相关生活质量的因素:单中心横断面研究

DOI:
10.1007/s11255-022-03180-x
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发表时间:
2022
影响因子:
2
通讯作者:
Takayuki Fujii
Takayuki Fujii
中科院分区:
医学4区
文献类型:
--
作者:
Aki Tabata;Hiroki Yabe;Takehide Katogi;Tomoya Yamaguchi;Yuya Mitake;Oono Shunta;Tomohiro Shirai;Takayuki Fujii

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研究背景健康相关生活质量(HRQoL)评估对慢性肾脏病(CKD)患者具有重要意义。然而,很少有研究检查与HRQoL相关的因素,如透析前CKD老年患者的身体功能。本研究评估了身体功能,肾功能和营养状况之间的关系,对HRQoL在this patient group.MethodsThis横断面研究包括61例年龄≥ 65岁的阶段3-5透析前CKD谁承认CKD教育的目的。使用EuroQoL五维五水平(EQ-5D-5L)健康状况测量,调查每个EQ-5D-5L项目的百分比。使用短体能测试组合(SPPB)和握力测量身体功能,并对年龄、性别、糖尿病、估计肾小球滤过率和老年营养风险指数等特征进行调查。与EQ-5D-5L相关的因素,确定使用多元回归analysis.ResultsMore一半以上的受访者(34/61,55.7%)选择了第二个或更高级别的“有问题”的疼痛/不适部分。EQ-5D-5L评分与握力(r= 0.34,p = 0.01)和SPPB(r= 0.59,p = 0.00)显著相关。在调整了握力、SPPB、年龄、性别、糖尿病和估计的肾小球滤过率后,只有SPPB(β= 0.67,p = 0.00)仍然是影响HRQoL的重要因素。
BackgroundHealth-related quality of life (HRQoL) assessment is important for patients with chronic kidney disease (CKD). However, few studies have examined factors related to HRQoL, such as physical function, in older patients with predialysis CKD. This study evaluated the relationship between physical function, renal function, and nutritional status on the HRQoL in this patient group.MethodsThis cross-sectional study included 61 patients aged ≥ 65 years with stages 3–5 predialysis CKD who were admitted for CKD education purposes. Using the EuroQoL 5-dimension 5-level (EQ-5D-5L) health status measure, the percentages of each EQ-5D-5L item were investigated. Physical function was measured using the short physical performance battery (SPPB) and grip strength, and characteristics, such as age, sex, diabetes mellitus, estimated glomerular filtration rate, and Geriatric Nutrition Risk Index, were investigated. Factors associated with EQ-5D-5L were identified using multiple regression analysis.ResultsMore than half of respondents (34/61, 55.7%) selected the second or higher level “have a problem” for the pain/discomfort section. The EQ-5D-5L score was significantly correlated with grip strength (r= 0.34,p= 0.01) and SPPB (r= 0.59,p= 0.00) in a single correlation analysis. Only SPPB (β= 0.67,p= 0.00) remained a significant factor after adjustment for grip strength, SPPB, age, sex, diabetes mellitus, and estimated glomerular filtration rate.ConclusionPhysical function may be an important factor influencing HRQoL in older patients with predialysis CKD.
SPPB 作为筛查晚期慢性肾病患者功能能力的方法有用吗?
DOI: 10.1016/j.nefroe.2019.01.010
发表时间: 2019
期刊: Nefrología (English Edition)
影响因子: --
作者:
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发表时间: 2020-12
影响因子: 6
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Krishnan A;Teixeira-Pinto A;Lim WH;Howard K;Chapman JR;Castells A;Roger SD;Bourke MJ;Macaskill P;Williams G;Lok CE;Diekmann F;Cross N;Sen S;Allen RDM;Chadban SJ;Pollock CA;Turner R;Tong A;Yang JYH;Williams N;Au E;Kieu A;James L;Francis A;Wong G;Craig JC
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DOI: 10.1007/s11255-020-02559-y
发表时间: 2020-07-13
影响因子: 2
作者:
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通讯作者: Lee, Dong-Young
DOI: 10.1681/asn.2012070702
发表时间: 2013-05-01
影响因子: 13.6
作者:
Roshanravan, Baback;Robinson-Cohen, Cassianne;Seliger, Stephen
通讯作者: Seliger, Stephen