Eight new peptaibols from sponge-associated Trichoderma atroviride.
Eight new peptaibols from sponge-associated Trichoderma atroviride.
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DOI：
10.3390/md11124937
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发表时间：
2013-12-11
期刊：
影响因子：
5.4
通讯作者：
Carmeli S
中科院分区：
文献类型：
--
作者：
Panizel I;Yarden O;Ilan M;Carmeli S
从从以色列东地中海沿岸采集的Axinellid海绵中培养的真菌菌株Trichoderma atroviride（NF 16）中分离出8种新的和4种已知的peptaidase。采用HRMS、MS/MS和一维和二维NMR测量确定了纯化合物的结构。分离的化合物属于trichorzianines，一个19-残基线性疏水肽家族，含有高比例的α-氨基异丁酸（Aib）、乙酰化的N-末端和C-末端氨基醇。这些新的肽对从以色列地中海沿岸分离的环境细菌表现出抗微生物活性。
Eight new and four known peptaibols were isolated from a strain of the fungus, Trichoderma atroviride (NF16), which was cultured from an Axinellid sponge collected from the East Mediterranean coast of Israel. The structures of the pure compounds were determined using HRMS, MS/MS and one- and two-dimensional NMR measurements. The isolated compounds belong to the trichorzianines, a family of 19-residue linear hydrophobic peptides containing a high proportion of α-aminoisobutyric acid (Aib), an acetylated N-terminus and a C-terminal amino alcohol. These new peptaibols exhibited antimicrobial activity against environmental bacteria isolated from the Mediterranean coast of Israel.
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影响因子：
4.4
作者：
Gal-Hemed, Inbal;Atanasova, Lea;Yarden, Oded
通讯作者：
Yarden, Oded
影响因子：
2
作者：
Sabareesh, V;Balaram, P
通讯作者：
Balaram, P
影响因子：
15
作者：
BODO, B;REBUFFAT, S;DAVOUST, D
通讯作者：
DAVOUST, D
DOI：
10.1007/bf02908688
发表时间：
1984-01-01
期刊：
CARLSBERG RESEARCH COMMUNICATIONS
影响因子：
--
作者：
MARFEY, P
通讯作者：
MARFEY, P
影响因子：
20.3
作者：
Paz, Z.;Komon-Zelazowska, M.;Yarden, O.
通讯作者：
Yarden, O.