A Primer for Single-Cell Sequencing in Non-Model Organisms.
A Primer for Single-Cell Sequencing in Non-Model Organisms.
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DOI:
10.3390/genes13020380
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发表时间:
2022-02-19
期刊:
影响因子:
3.5
通讯作者:
Athrey GN
中科院分区:
文献类型:
--
作者:
Alfieri JM;Wang G;Jonika MM;Gill CA;Blackmon H;Athrey GN
Single-cell sequencing technologies have led to a revolution in our knowledge of the diversity of cell types, connections between biological levels of organization, and relationships between genotype and phenotype. These advances have mainly come from using model organisms; however, using single-cell sequencing in non-model organisms could enable investigations of questions inaccessible with typical model organisms. This primer describes a general workflow for single-cell sequencing studies and considerations for using non-model organisms (limited to multicellular animals). Importantly, single-cell sequencing, when further applied in non-model organisms, will allow for a deeper understanding of the mechanisms between genotype and phenotype and the basis for biological variation.
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影响因子:
48
作者:
Dong X;Zhang L;Milholland B;Lee M;Maslov AY;Wang T;Vijg J
通讯作者:
Vijg J
影响因子:
44.1
作者:
Guo J;Grow EJ;Mlcochova H;Maher GJ;Lindskog C;Nie X;Guo Y;Takei Y;Yun J;Cai L;Kim R;Carrell DT;Goriely A;Hotaling JM;Cairns BR
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Cairns BR
DOI:
10.1007/978-1-4939-9240-9_2
发表时间:
2019-01-01
期刊:
SINGLE CELL METHODS: SEQUENCING AND PROTEOMICS
影响因子:
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作者:
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通讯作者:
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影响因子:
46.9
作者:
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通讯作者:
Kitzman, Jacob O.
影响因子:
46.9
作者:
Ding, Jiarui;Adiconis, Xian;Levin, Joshua Z.
通讯作者:
Levin, Joshua Z.