SMART: recent updates, new developments and status in 2015.
SMART: recent updates, new developments and status in 2015.
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DOI：
10.1093/nar/gku949
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发表时间：
2015-01
影响因子：
14.9
通讯作者：
Bork P
中科院分区：
文献类型：
--
作者：
Letunic I;Doerks T;Bork P
SMART（Simple Modular Architecture Research Tool）是一个网络资源（http：//smart.embl.de/），提供蛋白质结构域的简单识别和广泛注释以及蛋白质结构域结构的探索。在当前版本中，SMART包含了1200多个蛋白质结构域的手动策划模型，自我们上次更新文章以来，有2000个新模型。基础蛋白质数据库与UniProt，Ensembl和STRING同步，使注释结构域和其他蛋白质特征的总数超过1亿。SMART的“基因组”模式，从完全测序的基因组中注释蛋白质，大大扩展，现在包括2031个物种，而上一版本为1133个。SMART分析结果页面已完全重新设计，并包含指向几个新信息源的链接。一个新的，基于矢量的显示引擎已经在SMART中开发了蛋白质示意图，它也可以导出为高分辨率位图图像，以方便包含到其他文档中。SMART中的分类树显示已得到显著改进，并且可以使用集成搜索引擎轻松导航。
SMART (Simple Modular Architecture Research Tool) is a web resource (http://smart.embl.de/) providing simple identification and extensive annotation of protein domains and the exploration of protein domain architectures. In the current version, SMART contains manually curated models for more than 1200 protein domains, with ∼200 new models since our last update article. The underlying protein databases were synchronized with UniProt, Ensembl and STRING, bringing the total number of annotated domains and other protein features above 100 million. SMART's ‘Genomic’ mode, which annotates proteins from completely sequenced genomes was greatly expanded and now includes 2031 species, compared to 1133 in the previous release. SMART analysis results pages have been completely redesigned and include links to several new information sources. A new, vector-based display engine has been developed for protein schematics in SMART, which can also be exported as high-resolution bitmap images for easy inclusion into other documents. Taxonomic tree displays in SMART have been significantly improved, and can be easily navigated using the integrated search engine.
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影响因子：
14.9
作者：
Hunter S;Jones P;Mitchell A;Apweiler R;Attwood TK;Bateman A;Bernard T;Binns D;Bork P;Burge S;de Castro E;Coggill P;Corbett M;Das U;Daugherty L;Duquenne L;Finn RD;Fraser M;Gough J;Haft D;Hulo N;Kahn D;Kelly E;Letunic I;Lonsdale D;Lopez R;Madera M;Maslen J;McAnulla C;McDowall J;McMenamin C;Mi H;Mutowo-Muellenet P;Mulder N;Natale D;Orengo C;Pesseat S;Punta M;Quinn AF;Rivoire C;Sangrador-Vegas A;Selengut JD;Sigrist CJ;Scheremetjew M;Tate J;Thimmajanarthanan M;Thomas PD;Wu CH;Yeats C;Yong SY
通讯作者：
Yong SY
影响因子：
14.9
作者：
Minguez P;Letunic I;Parca L;Bork P
通讯作者：
Bork P
影响因子：
14.9
作者：
Flicek P;Amode MR;Barrell D;Beal K;Billis K;Brent S;Carvalho-Silva D;Clapham P;Coates G;Fitzgerald S;Gil L;Girón CG;Gordon L;Hourlier T;Hunt S;Johnson N;Juettemann T;Kähäri AK;Keenan S;Kulesha E;Martin FJ;Maurel T;McLaren WM;Murphy DN;Nag R;Overduin B;Pignatelli M;Pritchard B;Pritchard E;Riat HS;Ruffier M;Sheppard D;Taylor K;Thormann A;Trevanion SJ;Vullo A;Wilder SP;Wilson M;Zadissa A;Aken BL;Birney E;Cunningham F;Harrow J;Herrero J;Hubbard TJ;Kinsella R;Muffato M;Parker A;Spudich G;Yates A;Zerbino DR;Searle SM
通讯作者：
Searle SM
影响因子：
5.6
作者：
KROGH, A;BROWN, M;HAUSSLER, D
通讯作者：
HAUSSLER, D
影响因子：
14.9
作者：
Letunic I;Doerks T;Bork P
通讯作者：
Bork P