A Novel Minidumbbell DNA-Based Sensor for Silver Ion Detection.
A Novel Minidumbbell DNA-Based Sensor for Silver Ion Detection.
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DOI:
10.3390/bios13030358
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发表时间:
2023-03-08
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Silver ion (Ag+) is one of the most common heavy metal ions that cause environmental pollution and affect human health, and therefore, its detection is of great importance in the field of analytical chemistry. Here, we report an 8-nucleotide (nt) minidumbbell DNA-based sensor (M-DNA) for Ag+ detection. The minidumbbell contained a unique reverse wobble C·C mispair in the minor groove, which served as the binding site for Ag+. The M-DNA sensor could achieve a detection limit of 2.1 nM and sense Ag+ in real environmental samples with high accuracy. More importantly, the M-DNA sensor exhibited advantages of fast kinetics and easy operation owing to the usage of an ultrashort oligonucleotide. The minidumbbell represents a new and minimal non-B DNA structural motif for Ag+ sensing, allowing for the further development of on-site environmental Ag+ detection devices.
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DOI:
10.1007/s00604-017-2460-4
发表时间:
2017-11
期刊:
Mikrochimica acta
影响因子:
--
作者:
Guo Z;Zheng Y;Xu H;Zheng B;Qiu W;Guo Z
通讯作者:
Guo Z
影响因子:
4.9
作者:
Liu, Meng;Zhao, Huimin;Quan, Xie
通讯作者:
Quan, Xie
影响因子:
4.9
作者:
Lin, Yen-Hsiu;Tseng, Wei-Lung
通讯作者:
Tseng, Wei-Lung
影响因子:
15
作者:
Lee, Jung Heon;Wang, Zidong;Liu, Juewen;Lu, Yi
通讯作者:
Lu, Yi
影响因子:
4.3
作者:
Feichtmeier, Nadine S.;Leopold, Kerstin
通讯作者:
Leopold, Kerstin