ZFIN: enhancements and updates to the Zebrafish Model Organism Database.

ZFIN: enhancements and updates to the Zebrafish Model Organism Database.
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DOI:
10.1093/nar/gkq1077
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发表时间:
2011-01
影响因子:
14.9
通讯作者:
Westerfield M
Westerfield M
中科院分区:
生物学2区
文献类型:
--
作者:
Bradford Y;Conlin T;Dunn N;Fashena D;Frazer K;Howe DG;Knight J;Mani P;Martin R;Moxon SA;Paddock H;Pich C;Ramachandran S;Ruef BJ;Ruzicka L;Bauer Schaper H;Schaper K;Shao X;Singer A;Sprague J;Sprunger B;Van Slyke C;Westerfield M

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ZFIN,斑马鱼模型生物数据库,http://zfin.org,作为斑马鱼遗传,基因组,表型和发育数据的中央存储库和网络资源。ZFIN手动管理斑马鱼基因,表型,基因型,基因表达,抗体,解剖结构和出版物的综合数据。广泛的基于web的搜索表单和工具集合有助于访问这些数据的集成视图,从而促进分析和科学发现。ZFIN中的数据来自三个主要来源:斑马鱼出版物的管理、个人研究实验室和与生物信息学组织的合作。数据格式包括文本、图像和图形表示。ZFIN是一个动态资源,每天都会添加数据,这是我们持续管理过程的一部分。软件更新频繁。在这里,我们描述了ZFIN最近增加的内容,包括(i)增强的图像访问,(ii)基因组特征,(iii)基因组浏览器,(iv)转录本,(v)抗体和(vi)协议和抗体的社区wiki。
ZFIN, the Zebrafish Model Organism Database, http://zfin.org, serves as the central repository and web-based resource for zebrafish genetic, genomic, phenotypic and developmental data. ZFIN manually curates comprehensive data for zebrafish genes, phenotypes, genotypes, gene expression, antibodies, anatomical structures and publications. A wide-ranging collection of web-based search forms and tools facilitates access to integrated views of these data promoting analysis and scientific discovery. Data represented in ZFIN are derived from three primary sources: curation of zebrafish publications, individual research laboratories and collaborations with bioinformatics organizations. Data formats include text, images and graphical representations. ZFIN is a dynamic resource with data added daily as part of our ongoing curation process. Software updates are frequent. Here, we describe recent additions to ZFIN including (i) enhanced access to images, (ii) genomic features, (iii) genome browser, (iv) transcripts, (v) antibodies and (vi) a community wiki for protocols and antibodies.
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