Effect of Adjuvant Hormonal Therapy on the Development of Pulmonary Fibrosis after Postoperative Radiotherapy for Breast Cancer.
Effect of Adjuvant Hormonal Therapy on the Development of Pulmonary Fibrosis after Postoperative Radiotherapy for Breast Cancer.
复制标题
DOI：
10.4048/jbc.2020.23.e48
复制
发表时间：
2020-10
影响因子：
2.4
通讯作者：
Marinko T
中科院分区：
文献类型：
--
作者：
Anzic M;Marinko T
乳腺癌是妇女中最常见的恶性肿瘤。因此，研究乳腺癌肿瘤治疗的不良反应是至关重要的，其中一个不良反应是肺纤维化（PF）。PF是一种不可逆的疾病，可显著降低生活质量。在乳房肿瘤切除术后，放射治疗是乳腺癌的标准辅助治疗。此外，激素受体阳性乳腺癌用辅助激素疗法治疗。虽然放射治疗是PF的已知原因之一，但激素治疗对其发展的影响尚未明确。一些研究表明，伴随内分泌治疗，主要是他莫昔芬，和放疗可能会加强PF的发展。然而，关于激素治疗的时间管理方面的指导方针辅助放疗没有明确定义。本综述旨在提供一个全面的概述，现有的信息，激素治疗的效果，其管理时间方面的辅助放疗PF的发病率。
Breast cancer is the most common malignancy among women. Therefore, it is of paramount importance to study the adverse effects of oncological treatment of breast cancer, with one of adverse effects being pulmonary fibrosis (PF). PF is an irreversible condition and can significantly reduce the quality of life. Following lumpectomy, radiotherapy is the standard adjuvant treatment for breast cancer. Additionally, hormone receptor-positive breast cancers are treated with adjuvant hormonal therapy. While radiotherapy is one of the known causes of PF, the effect of hormone therapy on its development is not well-defined. Some studies have shown that the concomitant administration of endocrine therapy, primarily tamoxifen, and irradiation may potentiate the development of PF. However, guidelines regarding the timing of hormone therapy administration with respect to adjuvant radiotherapy are not clearly defined. This review aims to provide a comprehensive overview of the available information regarding the effect of hormone therapy and its timing of administration with respect to adjuvant radiotherapy on the incidence of PF.
登录
查看更多内容
影响因子：
51.1
作者：
Azria, David;Belkacemi, Yazid;Ozsahin, Mahmut
通讯作者：
Ozsahin, Mahmut
DOI：
10.1016/j.ijrobp.2009.06.091
发表时间：
2010-03-01
影响因子：
7
作者：
Marks, Lawrence B.;Bentzen, Soren M.;Deasy, Joseph O.;Kong, Feng-Ming (Spring);Bradley, Jeffrey D.;Vogelius, Ivan S.;El Naqa, Issam;Hubbs, Jessica L.;Lebesque, Joos V.;Timmerman, Robert D.;Martel, Mary K.;Jackson, Andrew
通讯作者：
Jackson, Andrew
影响因子：
9.6
作者：
Green, FHY
通讯作者：
Green, FHY
影响因子：
5.7
作者：
Koc, M;Polat, P;Suma, S
通讯作者：
Suma, S
影响因子：
3.9
作者：
Bese, Nuran Senel;Umay, Cenk;Ober, Ahmet
通讯作者：
Ober, Ahmet