Factors associated with untreated diabetes: analysis of data from 20,496 participants in the Japanese National Health and Nutrition Survey.
Factors associated with untreated diabetes: analysis of data from 20,496 participants in the Japanese National Health and Nutrition Survey.
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与未经治疗的糖尿病相关的因素：日本国家健康和营养调查中20,496名参与者的数据分析。
DOI：
10.1371/journal.pone.0118749
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发表时间：
2015
期刊：
影响因子：
3.7
通讯作者：
Noda M
中科院分区：
文献类型：
--
作者：
Goto M;Goto A;Ikeda N;Noda H;Shibuya K;Noda M
我们的目的是在一个具有全国代表性的日本人群样本中研究与未经治疗的糖尿病相关的因素。我们汇总了2005年至2009年日本国民健康和营养调查的数据（n = 20，496）。年龄在20岁及以上的人被纳入分析。如果受试者的HbA 1c水平≥6.5%（≥48 mmol/mol），我们将其归类为糖尿病。自我报告目前没有接受糖尿病治疗的糖尿病患者被认为是未经治疗的。我们进行了多项逻辑回归分析，以确定与未治疗的糖尿病相对于非糖尿病个体的相关因素。在纳入分析的20，496名参与者中，748人（3.6%）患有未经治疗的糖尿病。在未经治疗的糖尿病患者中，48.3%的患者既往被诊断为糖尿病，46.5%的患者HbA 1c水平≥7.0%（≥53 mmol/mol）。与非糖尿病参与者相比，未接受治疗的糖尿病参与者更有可能是男性，老年人，目前吸烟，具有较低的HDL胆固醇水平和较高的BMI，非HDL胆固醇水平和收缩压。在日本，有相当一部分未经治疗的糖尿病患者血糖控制不佳。在筛查项目中针对未治疗糖尿病的相关因素可能有效地加强糖尿病的治疗和控制。
We aimed to examine factors associated with untreated diabetes in a nationally representative sample of the Japanese population. We pooled data from the Japanese National Health and Nutrition Survey from 2005 to 2009 (n = 20,496). Individuals aged 20 years and older were included in the analysis. We classified participants as having diabetes if they had HbA1c levels ≥6.5% (≥48 mmol/mol). People with diabetes who self-reported that they were not currently receiving diabetic treatment were considered to be untreated. We conducted a multinomial logistic regression analysis to determine factors associated with untreated diabetes relative to non-diabetic individuals. Of 20,496 participants who were included in the analysis, untreated diabetes was present in 748 (3.6%). Among participants with untreated diabetes, 48.3% were previously diagnosed with diabetes, and 46.5% had HbA1c levels ≥7.0% (≥53 mmol/mol). Participants with untreated diabetes were significantly more likely than non-diabetic participants to be male, older, and currently smoking, have lower HDL cholesterol levels and higher BMI, non-HDL cholesterol levels, and systolic blood pressure. A substantial proportion of people in Japan with untreated diabetes have poor glycemic control. Targeting relevant factors for untreated diabetes in screening programs may be effective to enhance the treatment and control of diabetes.
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影响因子：
4.7
作者：
Nakamura M;Kiyama M;Kitamura A;Ishikawa Y;Sato S;Noda H;Yoshiike N
通讯作者：
Yoshiike N
影响因子：
4.4
作者：
Katanoda, K;Nitta, H;Matsumura, Y
通讯作者：
Matsumura, Y
影响因子：
1.6
作者：
Katanoda, K;Matsumura, Y
通讯作者：
Matsumura, Y
影响因子：
16.2
作者：
Huang, Elbert S.;Brown, Sydney F. S.;Meltzer, David O.
通讯作者：
Meltzer, David O.
影响因子：
4.6
作者：
Tekumit, Hayrettin;Cenal, Ali Riza;Akinci, Esat
通讯作者：
Akinci, Esat