Rotating-frame relaxation studies of slow motions in fluorinated phospholipid model membranes.
Rotating-frame relaxation studies of slow motions in fluorinated phospholipid model membranes.
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氟化磷脂模型膜中慢运动的旋转框架弛豫研究。
DOI：
10.1016/s0006-3495(88)82933-3
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发表时间：
1988
影响因子：
3.4
通讯作者：
Ho,C
中科院分区：
文献类型：
--
作者：
Peng,ZY;Simplaceanu,V;Lowe,IJ;Ho,C
在19 F标记的二肉豆蔻酰磷脂酰胆碱模型膜上进行了旋转框架弛豫实验。脂质在2-酰基链的4-、8-或12-位用单个CF2基团标记。定向脂质双层和多层脂质体已被研究。松弛率已被测量为锁定场强度，样品取向，标签的位置，和温度的函数。我们的结果证实了广泛的慢运动存在于双层和主导低频弛豫。弛豫速率对标签位置非常敏感。然而，对于所有三种脂质异构体，松弛的许多其他特征非常相似。多层脂质体的弛豫速率的温度依赖性不同于定向双层，这可能意味着运动也不同。为了拟合我们的数据，工作模型的各向异性重取向项和指向矢波动项的叠加组成的已被提出。我们还证实了几乎所有的弛豫过程是由分子内相互作用的调制引起的。在此基础上，本文从分子水平上讨论了慢运动的观点。
Rotating-frame relaxation experiments have been carried out on 19F-labeled dimyristoylphosphatidylcholine model membranes. The lipids are labeled with a single CF2 group in the 4-, 8-, or 12-position of the 2-acyl chain. Both oriented lipid bilayers and multilamellar liposomes have been investigated. The relaxation rate has been measured as a function of the locking-field strength, the sample orientation, the label position, and the temperature. Our results have confirmed that extensive slow motions exist in the bilayer and dominate the low-frequency relaxation. The relaxation rate is quite sensitive to the label position. However, many other features of the relaxation are very similar for all three lipid isomers. The temperature dependence of the relaxation rate for the multilamellar liposomes differs from the oriented bilayers, which may imply that the motions are also different. To fit our data, a working model consisting of a superposition of an anisotropic reorientation term and a director fluctuation term has been proposed. We have also verified that almost all of the relaxation process is caused by modulations of the intramolecular interactions. Based on this, a view of the slow motions at a molecular level is discussed in this paper.
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归因、脆弱性和心理调整：以乳腺癌为例。
DOI：
10.1037//0278-6133.4.6.521
发表时间：
1985
期刊：
Health psychology : official journal of the Division of Health Psychology, American Psychological Association
影响因子：
--
作者：
C. Timko;R. Janoff
通讯作者：
R. Janoff
影响因子：
3.9
作者：
JANOFFBULMAN, R;FRIEZE, IH
通讯作者：
FRIEZE, IH
心脏病发作后的因果归因、感知益处和发病率：一项为期 8 年的研究。
影响因子：
5.9
作者：
G. Affleck;H. Tennen;S. Croog;S. Levine
通讯作者：
S. Levine
DOI：
--
发表时间：
1971
期刊：
Social Science & Medicine (1967)
影响因子：
--
作者：
E. Markson
通讯作者：
E. Markson