Free-breathing cardiac MR stress perfusion with real-time slice tracking.

Free-breathing cardiac MR stress perfusion with real-time slice tracking.
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DOI:
10.1002/mrm.24977
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发表时间:
2014-09
影响因子:
3.3
通讯作者:
Nezafat, Reza
Nezafat, Reza
中科院分区:
医学3区
文献类型:
--
作者:
Basha, Tamer A.;Roujol, Sebastien;Kissinger, Kraig V.;Goddu, Beth;Berg, Sophie;Manning, Warren J.;Nezafat, Reza

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To develop a free-breathing cardiac MR perfusion sequence with slice tracking for use after physical exercise. We propose to use a leading navigator, placed immediately before each 2D slice acquisition, for tracking the respiratory motion and updating the slice location in real-time. The proposed sequence was used to acquire CMR perfusion datasets in 12 healthy adult subjects and 8 patients. Images were compared with the conventional perfusion (i.e. without slice tracking) results from the same subjects. The location and geometry of the myocardium were quantitatively analyzed, and the perfusion signal curves were calculated from both sequences to show the efficacy of the proposed sequence. The proposed sequence was significantly better compared to the conventional perfusion sequence in terms of qualitative image scores. Changes in the myocardial location and geometry decreased by ~50% in the slice tracking sequence. Furthermore, the proposed sequence had signal curves that are smoother and less noisy. The proposed sequence significantly reduces the effect of the respiratory motion on the image acquisition in both rest and stress perfusion scans.
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