Gender differences in obstructive sleep apnea and treatment implications.
Gender differences in obstructive sleep apnea and treatment implications.
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DOI：
10.1016/j.smrv.2007.11.003
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发表时间：
2008-12
影响因子：
10.5
通讯作者：
Ancoli-Israel, Sonia
中科院分区：
文献类型：
--
作者：
Lin, Christine M.;Davidson, Terence M.;Ancoli-Israel, Sonia
阻塞性睡眠呼吸暂停是数百万美国人白天嗜睡的常见原因。它也是一种与高血压、心血管疾病、中风、日间嗜睡、机动车事故和生活质量下降的可能性增加相关的疾病。许多基于人群的研究表明，阻塞性睡眠呼吸暂停在男性中比女性更常见，这种差异在临床环境中往往很明显。有许多病理生理学差异表明为什么男性比女性更容易患上这种疾病。虽然确切的机制尚不清楚，但肥胖、上呼吸道解剖结构、呼吸控制、激素和衰老的差异都被认为是起作用的。本综述的目的是检查阻塞性睡眠呼吸暂停的性别差异的文献，并分析这些差异是否在致病机制影响诊断或治疗。
Obstructive sleep apnea is a common cause of daytime sleepiness for millions of Americans. It is also a disease associated with an increased likelihood of hypertension, cardiovascular disease, stroke, daytime sleepiness, motor vehicle accidents, and diminished quality of life. A number of population based studies have shown that obstructive sleep apnea is more common in men than in women and this discrepancy is often evident in the clinical setting. There are a number of pathophysiological differences to suggest why men are more prone to the disease than women. Although the exact mechanisms are unknown, differences in obesity, upper airway anatomy, breathing control, hormones, and aging are all thought to play a role. The purpose of this review was to examine the literature on gender differences in obstructive sleep apnea and to analyze whether or not these differences in pathogenic mechanisms affect diagnosis or treatment.
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影响因子：
5.9
作者：
BLOCK, AJ;WYNNE, JW;CANTOR, B
通讯作者：
CANTOR, B
影响因子：
0.9
作者：
Calaora-Tournadre, D.;Ragot, S.;Pierre, F.
通讯作者：
Pierre, F.
DOI：
10.1164/ajrccm/143.4_pt_1.810
发表时间：
1991-04-01
期刊：
AMERICAN REVIEW OF RESPIRATORY DISEASE
影响因子：
--
作者：
CHADWICK, GA;CROWLEY, P;MCNICHOLAS, WT
通讯作者：
MCNICHOLAS, WT
影响因子：
9.6
作者：
COLLINS, LC;HOBERTY, PD;PEIRIS, AN
通讯作者：
PEIRIS, AN
影响因子：
5.6
作者：
Faux, MD;Larkin, EK;Redline, S
通讯作者：
Redline, S