Daily associations between alcohol use and unprotected anal sex among heavy drinking HIV-positive men who have sex with men.
Daily associations between alcohol use and unprotected anal sex among heavy drinking HIV-positive men who have sex with men.
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DOI：
10.1007/s10461-014-0896-7
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发表时间：
2015-03
影响因子：
4.4
通讯作者：
Mayer, Kenneth H.
中科院分区：
文献类型：
--
作者：
Kahler, Christopher W.;Wray, Tyler B.;Pantalone, David W.;Kruis, Ryan D.;Mastroleo, Nadine R.;Monti, Peter M.;Mayer, Kenneth H.
在美国，男男性行为者（MSM）占新感染艾滋病毒的最大比例。酒精可能会增加无保护的肛交，从而促进艾滋病毒的传播，但很少有研究关注艾滋病毒阳性的男男性接触者的传播行为。本研究通过30天的时间轴回访，探讨了重度饮酒hiv阳性男男性接触者中酒精使用与性行为之间的日常联系。广义估计方程的结果表明，某一天饮酒越多，与任何艾滋病毒感染状态的伴侣发生无保护肛交的几率呈线性增加。然而，报告与艾滋病毒阴性或艾滋病毒状况不明的伴侣进行无保护肛交的几率呈曲线增长，主要发生在大量饮酒（12杯以上）的情况下。研究结果表明，大量饮酒会增加性行为的风险，而性行为有可能将艾滋病毒传播给其他男性。
Men who have sex with men (MSM) account for the largest proportion of new HIV infections in the United States. Alcohol may facilitate HIV transmission by increasing unprotected anal sex, but few studies have focused on transmission behaviors in HIV-positive MSM. This study explored daily associations between alcohol use and sexual behavior among heavy drinking HIV-positive MSM using a 30-day Timeline Followback interview. Results of generalized estimating equations indicated that greater alcohol consumption on a given day was associated with a linear increase in the odds of having unprotected anal sex with partners of any HIV status. However, the odds of reporting unprotected anal sex with HIV-negative or HIV-status unknown partners increased in a curvilinear fashion, occurring primarily at very heavy levels of use (12+ drinks). Results suggest that very heavy drinking increases the risk of engaging in sexual behavior that has the potential for transmitting HIV to other men.
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影响因子：
3.4
作者：
Greenfield, Thomas K.;Ye, Yu;Kranzler, Henry R.
通讯作者：
Kranzler, Henry R.
影响因子：
3.8
作者：
Maisto, Stephen A.;Palfai, Tibor;Vanable, Peter A.;Heath, Jessie;Woolf-King, Sarah E.
通讯作者：
Woolf-King, Sarah E.
影响因子：
4.4
作者：
Pantalone, David W.;Huh, David;Nelson, Kimberly M.;Pearson, Cynthia R.;Simoni, Jane M.
通讯作者：
Simoni, Jane M.
影响因子：
168.9
作者：
Beyrer, Chris;Baral, Stefan D.;van Griensven, Frits;Goodreau, Steven M.;Chariyalertsak, Suwat;Wirtz, Andrea L.;Brookmeyer, Ron
通讯作者：
Brookmeyer, Ron
影响因子：
3.1
作者：
Leigh, BC
通讯作者：
Leigh, BC