Evidence for characteristic vascular patterns in solid tumours: quantitative studies using corrosion casts.
Evidence for characteristic vascular patterns in solid tumours: quantitative studies using corrosion casts.
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DOI：
10.1038/sj.bjc.6690416
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发表时间：
1999-05
影响因子：
8.8
通讯作者：
Denekamp, J
中科院分区：
文献类型：
--
作者：
Konerding, MA;Malkusch, W;Klapthor, B;van Ackern, C;Fait, E;Hill, SA;Parkins, C;Chaplin, DJ;Presta, M;Denekamp, J
通过微血管腐蚀铸型检查了四种不同肿瘤细胞系（CaX，CaNT，SaS，HEC-1B）皮下移植到小鼠体内的血管结构，以确定是否存在不同肿瘤类型的特征性血管模式，以及它是否与两种正常组织（肌肉和肠道）显著不同。三维重建扫描电子显微镜图像用于定量测量。血管直径，血管间和分支间的距离显示肿瘤类型之间的差异很大，而分支的角度是相似的。在所有肿瘤中，血管直径的变异性显著高于正常组织。定量数据为肿瘤细胞自身决定的特征性血管网络提供了强有力的证据。© 1999癌症研究运动
The vascular architecture of four different tumour cell lines (CaX, CaNT, SaS, HEC-1B) transplanted subcutaneously in mice was examined by means of microvascular corrosion casting in order to determine whether there is a characteristic vascular pattern for different tumour types and whether it differs significantly from two normal tissues, muscle and gut. Three-dimensional reconstructed scanning electron microscope images were used for quantitative measurements. Vessel diameters, intervessel and interbranch distances showed large differences between tumour types, whereas the branching angles were similar. In all tumours, the variability of the vessel diameters was significantly higher than in normal tissue. The quantitative data provide strong evidence for a characteristic vascular network determined by the tumour cells themselves. © 1999 Cancer Research Campaign
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某些人类肺癌的组织学结构以及对放射疗法的可能影响。
影响因子：
8.8
作者：
THOMLINSON, R H;GRAY, L H
通讯作者：
GRAY, L H
影响因子：
3
作者：
FOLKMAN, J
通讯作者：
FOLKMAN, J
影响因子：
3.1
作者：
GERLOWSKI, LE;JAIN, RK
通讯作者：
JAIN, RK
DOI：
10.3109/02841868409136015
发表时间：
1984-01-01
期刊：
ACTA RADIOLOGICA ONCOLOGY
影响因子：
--
作者：
DENEKAMP, J
通讯作者：
DENEKAMP, J
影响因子：
2.5
作者：
FALK, B
通讯作者：
FALK, B