Phorbol ester-stimulated secretion in chicken ileum: role of arachidonic acid metabolism.
Phorbol ester-stimulated secretion in chicken ileum: role of arachidonic acid metabolism.
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佛波酯刺激鸡回肠分泌：花生四烯酸代谢的作用。
DOI：
10.1016/0016-5085(90)91021-w
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发表时间：
1990
期刊：
影响因子：
29.4
通讯作者：
Chang,EB
中科院分区：
文献类型：
--
作者：
Musch,MW;Nahkla,AM;Chang,EB
Phorbol 12,13-dibutyrate, an activator of protein kinase C, stimulates electrogenic anion secretion in chicken ileum. This effect can be inhibited by the cyclooxygenase inhibitor piroxicam, suggesting arachidonic acid metabolites as mediators. Phorbol 12,13-dibutyrate stimulates increases in prostaglandin E2release and mucosal 3′,5′-cyclic adenosine monophosphate content in intact mucosa. Stimulation of prostaglandin E2release appears to come mainly from the subepithelial compartment and not from epithelial cells. Unlike its effect on anion secretion, phorbol 12,13-dibutyrate inhibition of sodium uptake by sodium-hydrogen exchange in isolated mature villus enterocytes is not inhibited by piroxicam. This study concludes that phorbol ester effects on anion secretion in chickens appear to be mediated by arachidonic acid metabolites most likely produced by cells of the lamina propria and submucosa, whereas phorbol ester effects on inhibiting upper villus cell sodium-hydrogen exchange may be a direct effect of phorbol esters.
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两种来源的花生四烯酸用于小鼠腹膜巨噬细胞氧化代谢的证据。
DOI：
10.1016/s0021-9258(19)68075-0
发表时间：
1982
期刊：
The Journal of biological chemistry
影响因子：
--
作者：
J. Humes;S. Sadowski;M. Galavage;M. Goldenberg;E. Subers;R. Bonney;F. Kuehl
通讯作者：
F. Kuehl
豚鼠结肠炎免疫模型中花生四烯酸代谢增加
影响因子：
7.3
作者：
N. Boughton;B. Whittle
通讯作者：
B. Whittle
钙介导的环 AMP 对小肠 Na-H 交换的抑制。
DOI：
10.1152/ajpcell.1987.252.3.c315
发表时间：
1987
期刊：
The American journal of physiology
影响因子：
--
作者：
Semrad,CE;Chang,EB
通讯作者：
Chang,EB
蛋白激酶 C 作为肠道电解质转运调节剂的证据。
影响因子：
--
作者：
J. Fondacaro;L. S. Henderson
通讯作者：
L. S. Henderson
影响因子：
29.4
作者：
P. Sharon;W. Stenson
通讯作者：
P. Sharon;W. Stenson