Sex/Gender Differences in Screening for Autism Spectrum Disorder: Implications for Evidence-Based Assessment.
Sex/Gender Differences in Screening for Autism Spectrum Disorder: Implications for Evidence-Based Assessment.
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DOI：
10.1080/15374416.2018.1437734
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发表时间：
2019-11
期刊：
影响因子：
--
通讯作者：
Carpenter LA
中科院分区：
文献类型：
--
作者：
Evans SC;Boan AD;Bradley C;Carpenter LA
自闭症谱系障碍 (ASD) 在男孩中的诊断率高于女孩；然而，人们对这种性别差异的性质或它与诊断评估实践的关系知之甚少。本研究考察了社交沟通问卷 (SCQ) 在男孩和女孩筛查自闭症谱系障碍 (ASD) 方面的表现。数据来自 SUCCESS 研究，这是一项针对 8-10 岁儿童自闭症谱系障碍患病率的人群研究。使用来自 3520 名儿童的 SCQ 数据进行分析，并使用来自 272 名 SCQ 分数较高的儿童的直接评估数据。基于 DSM-5 的两个 ASD 症状域的双因素模型与数据拟合得很好，并且对于女孩来说表现稍好一些。在一般人群样本中，女孩比男孩表现出更少的社交沟通/互动和限制性重复行为症状。然而，在直接评估样本中，患有自闭症谱系障碍的女孩比患有自闭症谱系障碍的男孩在社交沟通/互动方面表现出更大的障碍。总体而言，与 4-5 岁社交沟通/互动问题相关的项目是诊断效率最高的项目，尤其是对于女孩而言。同样，ROC 分析表明 SCQ 在男孩中表现良好，在女孩中表现良好。结果支持使用 SCQ 筛查自闭症谱系障碍，但并未表明性别/性别特异性截止点。与患有自闭症谱系障碍的男性同龄人和没有自闭症谱系障碍的女性同龄人相比，患有自闭症谱系障碍的女孩可能在社交沟通/互动方面表现出明显的个体内部缺陷。尽管还需要更多的研究，但仔细关注 4-5 岁左右的社交沟通/互动缺陷可能对于评估女孩的自闭症谱系障碍特别有用。
Autism spectrum disorder (ASD) is diagnosed more often in boys than in girls; however, little is known about the nature of this sex/gender discrepancy or how it relates to diagnostic assessment practices. The present study examines the performance of the Social Communication Questionnaire (SCQ) in screening for ASD among boys and girls. Data were drawn from the SUCCESS study, a population-based study of ASD prevalence among children 8-10 years of age. Analyses were conducted using SCQ data from 3520 children, with direct assessment data from 272 with elevated SCQ scores. A bifactor model based on DSM-5’s two ASD symptom domains fit the data well and performed slightly better for girls. In the general population sample, girls exhibited fewer social communication/interaction and restricted-repetitive behavior symptoms than boys. In the direct assessment sample, however, girls with ASD showed greater impairment in social communication/interaction than boys with ASD. Items pertaining to social communication/interaction problems at ages 4-5 were among the most diagnostically efficient overall and particularly for girls. Similarly, ROC analyses suggested that the SCQ performs adequately among boys and well among girls. Results support the use of the SCQ in screening for ASD but do not indicate sex/gender-specific cutoffs. Girls with ASD may exhibit pronounced intra-individual deficits in social communication/interaction compared to male peers with ASD and female peers without ASD. Although more research is needed, careful attention to social communication/interaction deficits around 4-5 years of age may be especially useful for assessing ASD in girls.
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影响因子：
4.7
作者：
Beggiato, Anita;Peyre, Hugo;Delorme, Richard
通讯作者：
Delorme, Richard
DOI：
10.1111/j.1469-7610.2007.01762.x
发表时间：
2007-09-01
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作者：
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作者：
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影响因子：
5.2
作者：
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通讯作者：
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