Narrow band imaging for the detection of gastric intestinal metaplasia and dysplasia during surveillance endoscopy.
Narrow band imaging for the detection of gastric intestinal metaplasia and dysplasia during surveillance endoscopy.
复制标题
DOI：
10.1007/s10620-010-1189-2
复制
发表时间：
2010-12
影响因子：
3.1
通讯作者：
Kuipers, Ernst J.
中科院分区：
文献类型：
--
作者：
Capelle, Lisette G.;Haringsma, Jelle;de Vries, Annemarie C.;Steyerberg, Ewout W.;Biermann, Katharina;van Dekken, Herman;Kuipers, Ernst J.
胃癌前病变的监测主要依靠随机活检取样。窄带成像（NBI）可以提高内镜监测肠上皮化生（IM）和异型增生的准确性。我们旨在比较NBI与白色光内镜（WLE）在监测IM和异型增生患者中的检出率。先前确定的胃IM或异型增生的患者进行了监测内窥镜检查。所有患者均在一次手术中进行了WLE和NBI。通过将内镜检查结果与组织学诊断相关联，计算WLE和NBI检测癌前病变的灵敏度。纳入43例患者（28例男性和15例女性，平均年龄59岁）。27例患者诊断为IM; 20例通过NBI和WLE检测，4例仅通过NBI检测，3例仅通过随机活检检测。通过WLE和NBI检测到7例异型增生，仅通过随机活检检测到2例异型增生。68例内镜检查发现的病变包含IM：47例通过WLE和NBI检测到，21例仅通过NBI检测到。9例内镜检查发现的病变显示发育异常：8例通过WLE和NBI检测到，1例仅通过NBI检测到。NBI和WLE检测癌前病变的敏感性、特异性、阳性和阴性预测值分别为71、58、65和65%和51、67、62和55%。与常规WLE相比，NBI提高了晚期胃癌前病变的诊断率。
Surveillance of premalignant gastric lesions relies mainly on random biopsy sampling. Narrow band imaging (NBI) may enhance the accuracy of endoscopic surveillance of intestinal metaplasia (IM) and dysplasia. We aimed to compare the yield of NBI to white light endoscopy (WLE) in the surveillance of patients with IM and dysplasia. Patients with previously identified gastric IM or dysplasia underwent a surveillance endoscopy. Both WLE and NBI were performed in all patients during a single procedure. The sensitivity of WLE and NBI for the detection of premalignant lesions was calculated by correlating endoscopic findings to histological diagnosis. Forty-three patients (28 males and 15 females, mean age 59 years) were included. IM was diagnosed in 27 patients; 20 were detected by NBI and WLE, four solely by NBI and three by random biopsies only. Dysplasia was detected in seven patients by WLE and NBI and in two patients by random biopsies only. Sixty-eight endoscopically detected lesions contained IM: 47 were detected by WLE and NBI, 21 by NBI only. Nine endoscopically detected lesions demonstrated dysplasia: eight were detected by WLE and NBI, one was detected by NBI only. The sensitivity, specificity, positive and negative predictive values for detection of premalignant lesions were 71, 58, 65 and 65% for NBI and 51, 67, 62 and 55% for WLE, respectively. NBI increases the diagnostic yield for detection of advanced premalignant gastric lesions compared to routine WLE.
登录
查看更多内容
影响因子：
7.7
作者：
Mayinger, B;Jordan, M;Hahn, EG
通讯作者：
Hahn, EG
影响因子：
9.3
作者：
Ohashi, A;Niwa, Y;Goto, H
通讯作者：
Goto, H
影响因子：
4.4
作者：
Lehours, Philippe;Yilmaz, Ozlem
通讯作者：
Yilmaz, Ozlem
影响因子：
9.3
作者：
Otsuka, Y;Niwa, Y;Goto, H
通讯作者：
Goto, H
影响因子：
9.3
作者：
Tajiri, H;Doi, T;Yagi, K
通讯作者：
Yagi, K