Average daily blood pressure, not office blood pressure, determines cardiac function in patients with hypertension.
Average daily blood pressure, not office blood pressure, determines cardiac function in patients with hypertension.
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决定高血压患者心脏功能的是每日平均血压，而不是诊室血压。
DOI：
10.1001/jama.1989.03420060089038
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发表时间：
1989
期刊：
影响因子：
--
通讯作者：
H. Dey
中科院分区：
文献类型：
--
作者：
W. White;P. Schulman;E. McCabe;H. Dey
为了确定医生和门诊血压不一致的高血压患者是否存在心脏病，我们前瞻性研究了三组年龄匹配的患者，这些患者通过偶然（门诊）和动态血压确定：（1）门诊血压大于140/90 mm Hg，清醒时动态血压为130/80 mm Hg或更低（2）办公室血压低于135/85 mm Hg且清醒动态血压为130/80 mm Hg或更低（血压正常者）;和（3）办公室血压高于140/90 mm Hg且清醒动态血压为140/90 mm Hg或更高（“日间”高血压者）。在办公室高血压患者中，左心房指数和左心室质量指数均显著低于日间高血压患者，与血压正常者无统计学差异。办公室高血压组静息时的左室充盈率和运动峰值时的射血分数显著高于日间高血压组，但与血压正常者无差异。这些发现表明，只有在医生办公室血压升高的患者心脏大小和功能与血压正常的人相似。因此，平均每日血压最能预测心脏终末器官损伤。
To determine the presence of cardiac disease in hypertensive patients with disparities between physician and out-of-office blood pressures, we prospectively studied three groups of age-matched patients identified by both casual (office) and ambulatory blood pressures: (1) office blood pressure greater than 140/90 mm Hg and awake ambulatory blood pressure of 130/80 mm Hg or less ("office" hypertensives); (2) office blood pressure less than 135/85 mm Hg and awake ambulatory blood pressure of 130/80 mm Hg or less (normotensives); and (3) office blood pressure greater than 140/90 mm Hg and awake ambulatory blood pressure of 140/90 mm Hg or greater ("daytime" hypertensives). In the patients with office hypertension, both the left atrial index and left ventricular mass index were significantly less than in patients with daytime hypertension and not statistically different from those of the normotensive subjects. Left ventricular filling rate at rest and ejection fraction at peak exercise were significantly greater in the office hypertensive group than in the daytime hypertensive group but were no different from those of the normotensive subjects. These findings demonstrate that patients with blood pressure elevation only in the physician's office have cardiac size and function similar to those of normotensive individuals. Thus, the average daily blood pressure best predicts cardiac end-organ damage.
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DOI：
10.1001/jama.1988.03720020027031
发表时间：
1988-01
期刊：
JAMA
影响因子：
--
作者：
T. Pickering;G. James;Charlene Boddie;G. Harshfield;S. Blank;J. Laragh
通讯作者：
T. Pickering;G. James;Charlene Boddie;G. Harshfield;S. Blank;J. Laragh
通过核心脏探针、放射性核素血管造影和造影电影血管造影测定的左心室舒张功能的比较。
DOI：
--
发表时间：
1986
期刊：
Journal of nuclear medicine : official publication, Society of Nuclear Medicine
影响因子：
--
作者：
Seals,AA;Verani,MS;Tadros,S;Mahmarian,JJ;Roberts,R
通讯作者：
Roberts,R
影响因子：
39.2
作者：
CASALE, PN;DEVEREUX, RB;LARAGH, JH
通讯作者：
LARAGH, JH
影响因子：
37.8
作者：
DEVEREUX, RB;PICKERING, TG;LARAGH, JH
通讯作者：
LARAGH, JH
左心室充盈异常：轻至中度全身性高血压的早期发现。
DOI：
10.1016/0002-9149(84)90695-7
发表时间：
1984
期刊：
The American journal of cardiology
影响因子：
--
作者：
Inouye,I;Massie,B;Loge,D;Topic,N;Silverstein,D;Simpson,P;Tubau,J
通讯作者：
Tubau,J