A cell type annotation Jamboree-Revival of а communal science forum.

A cell type annotation Jamboree-Revival of а communal science forum.
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DOI:
10.1002/dvg.23383
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发表时间:
2020-09
期刊:
Genesis (New York, N.Y. : 2000)
影响因子:
--
通讯作者:
Kirschner MW
Kirschner MW
中科院分区:
其他
文献类型:
--
作者:
Peshkin L;Kirschner MW

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目前正在为人体组织和几种模式生物构建细胞图谱。新技术使得在许多物种中创建庞大的数据集成为可能,但这些数据的价值关键取决于注释的质量。注释单细胞数据和创建跨生物体可比较的知识表示的工具一直落后。我们认为,成功创建细胞地图集将需要复兴训练营式的论坛,用于公共注释,并结合密集的学习研讨会,称为“Jamboree”。我们报告了我们在霍华德休斯医学研究所Janelia农场校园成功开发结构和课程并举办这种爪蟾胚胎细胞类型大聚会的经验。
Cell Atlases are currently being constructed for human tissues as well as several model organisms. New technologies make creation of vast datasets in many species possible, but the value of such data crucially depends on the quality of annotation. The tools of annotating single cell data and creating knowledge representations comparable across organisms have been lagging. We argue that successfully creating Cell Atlases will require a revival of a boot-camp style forum for communal annotation combined with an intensive learning workshop, dubbed a “Jamboree”. We report on our experience of successfully developing a structure and curriculum and running such a Jamboree for Xenopus Embryonic Cell Types at the Janelia Farms campus of the Howard Hughes Medical Institute.
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