Converging integration between ascending proprioceptive inputs and the corticospinal tract motor circuit underlying skilled movement control.

Converging integration between ascending proprioceptive inputs and the corticospinal tract motor circuit underlying skilled movement control.
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提升本体感觉输入与皮质脊髓束运动回路之间的融合整合是熟练运动控制的基础。

DOI:
10.1016/j.cophys.2020.10.007
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发表时间:
2021-03
影响因子:
2.5
通讯作者:
Yoshida Y
Yoshida Y
中科院分区:
其他
文献类型:
--
作者:
Kalambogias J;Yoshida Y

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上行本体感受传入和下行皮质脊髓束投射之间的会聚相互作用在熟练运动行为的调制和协调中是至关重要的。这些过程的基础是本体感受和皮质脊髓束信息在脑和脊髓中的功能输入和整合机制。在这篇综述中,我们首先强调皮质脊髓束运动回路和接受本体感受输入的脊髓中间神经元之间的关键联系。我们也将讨论皮质脊髓束进入脊髓突触前抑制系统及其在调节本体感受刺激中的作用。最后,我们将集中于皮质脊髓神经元对背柱核复合体的影响,背柱核复合体是处理上行体感信息的整合枢纽。
Converging interactions between ascending proprioceptive afferents and descending corticospinal tract projections are critical in the modulation and coordination of skilled motor behaviors. Fundamental to these processes are the functional inputs and the mechanisms of integration in the brain and spinal cord between proprioceptive and corticospinal tract information. In this review, we first highlight key connections between corticospinal tract motor circuit and spinal interneurons that receive proprioceptive inputs. We will also address corticospinal tract access to the presynaptic inhibitory system in the spinal cord and its role in modulating proprioceptive stimuli. Lastly, we will focus on the corticospinal neuron influences on the dorsal column nuclei complex, an integration hub for processing ascending somatosensory information.
DOI: 10.1113/jphysiol.1961.sp006798
发表时间: 1961-01-01
影响因子: 5.5
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