Relationship Between Age-Related Changes in Skeletal Muscle Mass and Physical Function: A Cross-Sectional Study of an Elderly Japanese Population.

Relationship Between Age-Related Changes in Skeletal Muscle Mass and Physical Function: A Cross-Sectional Study of an Elderly Japanese Population.
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DOI:
10.7759/cureus.24260
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发表时间:
2022-04
影响因子:
1.2
通讯作者:
Horie, Jun
Horie, Jun
中科院分区:
其他
文献类型:
--
作者:
Iwase, Hiroaki;Murata, Shin;Nakano, Hideki;Shiraiwa, Kayoko;Abiko, Teppei;Goda, Akio;Nonaka, Koji;Anami, Kunihiko;Horie, Jun

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骨骼肌质量与肌肉力量呈正相关,但握力与整体肌肉力量的关系存在争议。本研究的目的是明确不同年龄组的特定部位骨骼肌质量的变化,并确定日本社区居住老年人骨骼肌质量的特定部位、年龄相关变化与身体功能之间的关系。参与者被分为五年间隔的年龄组(65-69岁,70-74岁,75-79岁和≥80岁),并按性别分类。使用多频生物电阻抗分析仪(InBody 430(Biospace Co.,有限公司,首尔,韩国)和InBody 470(InBody Japan Inc.,东京,日本))。对于身体功能评估,我们测量了握力、股四头肌力量、仰卧起坐计数、坐位伸展距离和睁眼单腿站立时间,并进行了计时起立和行走(TUG)测试。结果表明,骨骼肌质量随着年龄的增长而下降,无论性别在所有测量的网站。此外,偏相关分析调整的年龄,体质,和有/无运动习惯显示,最高的相关性是骨骼肌质量在所有网站和握力之间。因此,即使在日本人中,监测握力也可用作全身骨骼质量的代表。
Skeletal muscle mass and muscle strength are positively correlated, but the relationship between grip strength and global muscle strength is controversial. This study aimed to clarify the changes in site-specific skeletal muscle mass by age group and determine the relationship between site-specific, age-related changes in skeletal muscle mass and physical function in community-dwelling elderly people in Japan. The participants were divided into age groups of five-year intervals (65-69 years, 70-74 years, 75-79 years, and ≥80 years) and were also categorized by sex. The skeletal muscle mass of the upper limbs, lower limbs, and trunk was measured using multifrequency bioelectrical impedance analyzers (InBody 430 (Biospace Co., Ltd., Seoul, Korea) and InBody 470 (InBody Japan Inc., Tokyo, Japan)). For physical function assessment, we measured grip strength, quadriceps strength, sit-up count, sit-and-reach distance, and standing time on one leg with eyes open and performed the timed up and go (TUG) test. The results showed that skeletal muscle mass decreased with age regardless of sex at all measured sites. Furthermore, a partial correlation analysis adjusted for age, physical constitution, and the presence/absence of exercise habits revealed that the highest correlation was between skeletal muscle mass in all sites and grip strength. Thus, monitoring grip strength may be used as a representative of systemic skeletal mass even in Japanese people.
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