Possible role of the gut microbiota in the pathogenesis of anorexia nervosa.

Possible role of the gut microbiota in the pathogenesis of anorexia nervosa.
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DOI:
10.1186/s13030-021-00228-9
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发表时间:
2021-11-29
影响因子:
2.1
通讯作者:
Sudo N
Sudo N
中科院分区:
医学4区
文献类型:
--
作者:
Sudo N

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神经性厌食症(AN)是一种饮食失调症,其特征是体重极度减轻和害怕体重增加。心理社会因素被认为在AN的发展和进展中起重要作用;然而,生物因素也可能导致进食障碍。最近的证据表明,肠道微生物群在神经精神疾病(包括AN)的发病机制中起着重要作用。在这篇文章中,我们描述了肠道微生物群在AN的发展和持续性中的可能作用,基于最新的研究工作,包括我们小组的研究工作。
Anorexia nervosa (AN), an eating disorder, is characterized by extreme weight loss and fear of weight gain. Psychosocial factors are thought to play important roles in the development and progression of AN; however, biological factors also presumably contribute to eating disorders. Recent evidence has shown that the gut microbiota plays an important role in pathogenesis of neuropsychiatric disorders including AN. In this article, we describe the possible role of the gut microbiota in the development and persistence of AN, based on the latest research works, including those of our group.
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