Perceptions, knowledge, and satisfaction with contralateral prophylactic mastectomy among young women with breast cancer: a cross-sectional survey.
Perceptions, knowledge, and satisfaction with contralateral prophylactic mastectomy among young women with breast cancer: a cross-sectional survey.
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DOI：
10.7326/0003-4819-159-6-201309170-00003
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发表时间：
2013-09-17
影响因子：
39.2
通讯作者：
Partridge AH
中科院分区：
文献类型：
--
作者：
Rosenberg SM;Tracy MS;Meyer ME;Sepucha K;Gelber S;Hirshfield-Bartek J;Troyan S;Morrow M;Schapira L;Come SE;Winer EP;Partridge AH
对侧预防性乳房切除术（CPM）的比率急剧增加，特别是在患有乳腺癌的年轻女性中，但对女性如何决定接受CPM知之甚少。研究选择CPM的年轻乳腺癌女性的偏好、知识、决策和经验。横截面调查。八个学术和社区医疗中心，在2006年11月至2010年11月期间，招募了550名40岁及以下被诊断患有乳腺癌的妇女。123名没有已知双侧乳腺癌的女性报告进行了双侧乳房切除术。一项一次性的23项调查，包括与决策、知识、风险认知和乳腺癌担忧相关的项目。大多数妇女（98%）表示，希望降低患对侧乳腺癌（CBC）的机会和提高生存率（94%）是决定接受CPM的极其或非常重要的因素。然而，只有18%的人表示，接受CPM的乳腺癌妇女比不接受CPM的妇女寿命更长。BRCA 1或BRCA 2突变携带者更准确地感知他们的CBC风险，而没有已知突变的女性大大高估了这种风险。这项调查的平均时间为术后两年，未经验证，有些问题可能被受访者误解或受到回忆偏差的影响。我们的研究结果的普遍性可能是有限的。尽管知道CPM并不能明显提高生存率，但接受过该手术的妇女这样做，部分原因是为了延长寿命。许多女性高估了她们未受影响的乳房患乳腺癌的实际风险。有必要采取干预措施，改善风险沟通，努力促进循证决策。
There has been a dramatic increase in rates of contralateral prophylactic mastectomy (CPM), particularly among younger women with breast cancer, however little is known about how women approach the decision to undergo CPM. To examine preferences, knowledge, decision-making, and experiences of young women with breast cancer who chose CPM. Cross-sectional survey. Eight academic and community medical centers that enrolled 550 women diagnosed with breast cancer at age 40 and younger, between November 2006 and November 2010. 123 women without known bilateral breast cancer who reported having a bilateral mastectomy. A one-time, 23 item survey that included items related to decision-making, knowledge, risk perception, and breast cancer worry. Most women (98%) indicated that the desire to lower the chance of developing a contralateral breast cancer (CBC) and to improve survival (94%) were extremely or very important factors in their decision to undergo CPM. However, only 18% indicated that women with breast cancer who undergo CPM live longer than women who do not. BRCA 1 or BRCA 2 mutation carriers more accurately perceived their risk of a CBC while women without a known mutation substantially overestimated this risk. The survey, administered a median of two years post-surgery, was not validated and some questions might have been misinterpreted by respondents or subject to recall bias. Generalizability of our findings might be limited. Despite knowing that CPM does not clearly improve survival, women who have undergone the procedure do so, in part, to extend their lives. Many women overestimate their actual risk of developing breast cancer in the unaffected breast. Interventions aimed at improving risk communication in an effort to promote evidence-based decision-making are warranted.
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影响因子：
3.8
作者：
Graves, Kristi D.;Peshkin, Beth N.;Schwartz, Marc D.
通讯作者：
Schwartz, Marc D.
影响因子：
3.7
作者：
Arrington, Amanda K.;Jarosek, Stephanie L.;Tuttle, Todd M.
通讯作者：
Tuttle, Todd M.
影响因子：
10.3
作者：
Hawley, Sarah T.;Griggs, Jennifer J.;Katz, Steven J.
通讯作者：
Katz, Steven J.
影响因子：
158.5
作者：
ADAMI, HO;MALKER, B;STONE, B
通讯作者：
STONE, B
影响因子：
5.8
作者：
Brewster, Abenaa M.;Parker, Patricia A.
通讯作者：
Parker, Patricia A.