An update on cancer- and chemotherapy-related cognitive dysfunction: current status.
An update on cancer- and chemotherapy-related cognitive dysfunction: current status.
复制标题
DOI：
10.1053/j.seminoncol.2011.03.014
复制
发表时间：
2011-06
影响因子：
4
通讯作者：
Morrow GR
中科院分区：
文献类型：
--
作者：
Janelsins MC;Kohli S;Mohile SG;Usuki K;Ahles TA;Morrow GR
本文综述了近年来有关癌症治疗相关认知障碍的文献，重点是化疗的影响。许多患者在癌症治疗期间和之后有认知困难，对一些人来说，在治疗后的最后几年。我们还不完全了解哪些因素会增加治疗期间认知困难的易感性，哪些因素会导致持续的问题。我们审查可能的贡献者，包括遗传和生物因素。我们主要关注的是乳腺癌辅助化疗对认知功能的影响，但也讨论了化疗对老年人和脑肿瘤患者的认知功能的影响。
The purpose of this review is to summarize the current literature on the effects of cancer treatment-related cognitive difficulties, with a focus on the effects of chemotherapy. Numerous patients have cognitive difficulties during and after cancer treatments and, for some, these last years after treatment. We do not yet fully understand which factors increase susceptibility to cognitive difficulties during treatment and which cause persistent problems. We review possible contributors, including genetic and biological factors. Mostly we focus is on cognitive effects of adjuvant chemotherapy for breast cancer; however, cognitive effects of chemotherapy on the elderly and brain tumor patients are also discussed.
登录
查看更多内容
DOI：
10.1046/j.1532-5415.2003.51465.x
发表时间：
2003-10-01
影响因子：
6.3
作者：
Borson, S;Scanlan, JM;Ganguli, M
通讯作者：
Ganguli, M
影响因子：
45.3
作者：
Ahles, Tim A.;Saykin, Andrew J.;Kaufman, Peter A.
通讯作者：
Kaufman, Peter A.
影响因子：
4.5
作者：
Green, HJ;Pakenham, KI;Gardiner, RA
通讯作者：
Gardiner, RA
影响因子：
45.3
作者：
Ahles, TA;Saykin, AJ;Silberfarb, PM
通讯作者：
Silberfarb, PM
影响因子：
6.2
作者：
Chen, HB;Cantor, A;Extermann, M
通讯作者：
Extermann, M